Overview

  • Product nameAnti-FOXG1 antibody
    See all FOXG1 primary antibodies
  • Description
    Rabbit polyclonal to FOXG1
  • Specificityab23470 reacts with Forkhead-Related Protein FKHL2 (FOXG1A).
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Human FOXG1 aa 271-325.
    Database link: P55316

  • Positive control
    • Jurkat cell lysate. Human liver and human kindney.

Properties

Applications

Our Abpromise guarantee covers the use of ab23470 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 5 - 8 µg/ml. Detects a band of approximately 58 kDa (predicted molecular weight: 51 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use at an assay dependent concentration.

Target

  • FunctionTranscription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon.
  • Tissue specificityExpression is restricted to the neurons of the developing telencephalon.
  • Involvement in diseaseDefects in FOXG1 are the cause of congenital variant of Rett syndrome (RTTCV) [MIM:613454]. RTTCV is a severe neurodevelopmental disorder with features of classic Rett syndrome but earlier onset in the first months of life. Clinical features include progressive microcephaly, hypotonia, irresponsiveness and irritability in the neonatal period, mental retardation, psychomotor regression and stereotypical movements.
  • Sequence similaritiesContains 1 fork-head DNA-binding domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • BF-1 antibody
    • BF-2 antibody
    • BF1 antibody
    • BF2 antibody
    • Brain factor 1 antibody
    • Brain factor 2 antibody
    • FHKL antibody
    • FKH2 antibody
    • FKHL1 antibody
    • FKHL2 antibody
    • FKHL3 antibody
    • FKHL4 antibody
    • Forkhead box protein G1 antibody
    • Forkhead box protein G1A antibody
    • Forkhead box protein G1B antibody
    • Forkhead box protein G1C antibody
    • Forkhead like 1 antibody
    • Forkhead like 2 antibody
    • Forkhead like 3 antibody
    • Forkhead like 4 antibody
    • Forkhead-related protein FKHL1 antibody
    • Forkhead-related protein FKHL2 antibody
    • Forkhead-related protein FKHL3 antibody
    • FOXG1 antibody
    • FOXG1_HUMAN antibody
    • FOXG1A antibody
    • FOXG1B antibody
    • FOXG1C antibody
    • HBF 1 antibody
    • HBF G2 antibody
    • hBF-2 antibody
    • HBF2 antibody
    • HFK1 antibody
    • HFK2 antibody
    • HFK3 antibody
    • KHL2 antibody
    • Oncogene QIN antibody
    • QIN antibody
    see all

Anti-FOXG1 antibody images

  • Anti-FOXG1 antibody (ab23470) at 2 µg/ml + Jurkat cell lysate

    Secondary
    HRP conjugated anti-Rabbit IgG

    Performed under reducing conditions.

    Predicted band size : 51 kDa
    Observed band size : 58 kDa (why is the actual band size different from the predicted?)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human liver tissue labelling FOXG1 with ab23470 at a concentration of 4-8µg/ml. Cells with positive label: Hepatocyte (indicated with arrows). Magnification: X400.

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human kidney tissue labelling FOXG1 with ab23470 at a concentration of 4-8µg/ml. Cells with positive labels (arrows) are Epithelial cells of renal tubule.

References for Anti-FOXG1 antibody (ab23470)

This product has been referenced in:
  • Rittschof CC  et al. Neuromolecular responses to social challenge: common mechanisms across mouse, stickleback fish, and honey bee. Proc Natl Acad Sci U S A 111:17929-34 (2014). IHC ; Mouse . Read more (PubMed: 25453090) »
  • Adesina AM  et al. FOXG1 is overexpressed in hepatoblastoma. Hum Pathol 38:400-9 (2007). IHC-P ; Human . Read more (PubMed: 17217994) »

See all 2 Publications for this product

Product Wall

Arthur,

This is probably the same list that you came up with, for Pax6 and synaptophysin we have abs that match the requirments:

Pax6
http://www.abcam.com/PAX6-antibody-Stem-Cell-Marker-ab5790.html

Synaptophysin
http:...

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Thank you for your response.

This is to let you know that I have placed a new order for you - for one vial of ab23470 as a free of charge replacement (exchange for the original ab86292) and the new order number is 1119742.

I hope th...

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I am very pleased to hear you would like to accept our offer and test these products in IF on chick. Each code will give you: 1 free PRIMARY ANTIBODY OR VALUE OFF OF ORDER before the expiration date. To redeem this offer, please submit an Abreview for ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"