Overview

  • Product name
  • Description
    Rabbit polyclonal to FOXH1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Horse, Cow, Cat
  • Immunogen

    Synthetic peptide corresponding to a region within N-terminal amino acids 1-50 (MGPCSGSRLG PPEAESPSQP PKRRKKRYLR HDKPPYTYLA MIALVIQAAP) of Human FOXH1 (NP_003914)

  • Positive control
    • HT1080 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab102590 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 39 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Contains 1 fork-head DNA-binding domain.
  • Domain
    The FM region is required for binding SMAD2/SMAD4 complexes. FM2 is more effective than FM1 and only interacts with phosphorylated SMAD2 that is in an activated SMAD complex.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • FAST 1 antibody
    • Fast 2 antibody
    • Fast-1 antibody
    • Fast-2 antibody
    • FAST1 antibody
    • Fast2 antibody
    • Forkhead activin signal transducer 1 antibody
    • Forkhead activin signal transducer 2 antibody
    • Forkhead box H1 antibody
    • Forkhead box protein H1 antibody
    • FOX H1 antibody
    • FOXH 1 antibody
    • FOXH1 antibody
    • FOXH1_HUMAN antibody
    • hFAST 1 antibody
    • hFAST-1 antibody
    • hFAST1 antibody
    • Human homolog of Xenopus forkhead activin signal transducer 1 antibody
    • TGF beta/Activin signal transducer FAST1 antibody
    see all

Images

  • Anti-FOXH1 antibody (ab102590) at 1 µg/ml + HT1080 Cell Lysate at 10 µg

    Predicted band size : 39 kDa

References

ab102590 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab102590.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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