Overview

  • Product name
  • Description
    Rabbit polyclonal to FOXM1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment within Human FOXM1 aa 1-282. The exact sequence is proprietary.
    Database link: Q08050

  • Positive control
    • 293T, A431, FOXM1-transfected 293T cells cell lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab184637 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 84 kDa.

Target

  • Function
    Transcriptional activatory factor. May play a role in the control of cell proliferation.
  • Tissue specificity
    Expressed in thymus, testis, small intestine, colon followed by ovary. Appears to be expressed only in adult organs containing proliferating/cycling cells or in response to growth factors. Also expressed in epithelial cell lines derived from tumors. Not expressed in resting cells. Isoform 2 is highly expressed in testis.
  • Sequence similarities
    Contains 1 fork-head DNA-binding domain.
  • Developmental stage
    Embryonic expression pattern: liver, lung, intestine, kidney, urinary tract; adult expression pattern: intestine, colon, testis and thymus.
  • Domain
    Within the protein there is a domain which acts as a transcriptional activator. Insertion of a splicing sequence within it inactivates this transcriptional activity, as it is the case for isoform 4.
  • Post-translational
    modifications
    Phosphorylated in M (mitotic) phase.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • FKHL16 antibody
    • Forkhead box M1 antibody
    • Forkhead box protein M1 antibody
    • forkhead like 16 antibody
    • Forkhead-related protein FKHL16 antibody
    • FOX M1 antibody
    • Foxm1 antibody
    • FOXM1_HUMAN antibody
    • FOXM1B antibody
    • Hepatocyte nuclear factor 3 forkhead homolog 11 antibody
    • HFH-11 antibody
    • HFH11 antibody
    • HNF-3/fork-head homolog 11 antibody
    • HNF3 antibody
    • INS1 antibody
    • M phase phosphoprotein 2 antibody
    • M-phase phosphoprotein 2 antibody
    • MPHOSPH2 antibody
    • MPM-2 reactive phosphoprotein 2 antibody
    • MPP2 antibody
    • PIG29 antibody
    • TGT3 antibody
    • Transcription factor Trident antibody
    • Trident antibody
    • WIN antibody
    • Winged-helix factor from INS-1 cells antibody
    • Winged-helix factor from INS1 cells antibody
    see all

Images

  • All lanes : Anti-FOXM1 antibody (ab184637) at 1/500 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : A431 whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 84 kDa



    7.5% SDS PAGE

  • All lanes : Anti-FOXM1 antibody (ab184637) at 1/5000 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : FOXM1 transfected 293T whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 84 kDa



    7.5% SDS PAGE

References

This product has been referenced in:
  • Smirnov A  et al. FOXM1 regulates proliferation, senescence and oxidative stress in keratinocytes and cancer cells. Aging (Albany NY) 8:1384-97 (2016). IHC-P ; Human . Read more (PubMed: 27385468) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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