Overview

  • Product nameAnti-FOXM1 antibody
    See all FOXM1 primary antibodies
  • Description
    Rabbit polyclonal to FOXM1
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to a region within amino acids 714-763 (ANRSLTEGLV LDTMNDSLSK ILLDISFPGL DEDPLGPDNI NWSQFIPELQ) of human FOXM1 (NP_068772).

  • Positive control
    • Jurkat cell lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab83097 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 84 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionTranscriptional activatory factor. May play a role in the control of cell proliferation.
  • Tissue specificityExpressed in thymus, testis, small intestine, colon followed by ovary. Appears to be expressed only in adult organs containing proliferating/cycling cells or in response to growth factors. Also expressed in epithelial cell lines derived from tumors. Not expressed in resting cells. Isoform 2 is highly expressed in testis.
  • Sequence similaritiesContains 1 fork-head DNA-binding domain.
  • Developmental stageEmbryonic expression pattern: liver, lung, intestine, kidney, urinary tract; adult expression pattern: intestine, colon, testis and thymus.
  • DomainWithin the protein there is a domain which acts as a transcriptional activator. Insertion of a splicing sequence within it inactivates this transcriptional activity, as it is the case for isoform 4.
  • Post-translational
    modifications
    Phosphorylated in M (mitotic) phase.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • FKHL16 antibody
    • Forkhead box M1 antibody
    • Forkhead box protein M1 antibody
    • forkhead like 16 antibody
    • Forkhead-related protein FKHL16 antibody
    • FOX M1 antibody
    • Foxm1 antibody
    • FOXM1_HUMAN antibody
    • FOXM1B antibody
    • Hepatocyte nuclear factor 3 forkhead homolog 11 antibody
    • HFH-11 antibody
    • HFH11 antibody
    • HNF-3/fork-head homolog 11 antibody
    • HNF3 antibody
    • INS1 antibody
    • M phase phosphoprotein 2 antibody
    • M-phase phosphoprotein 2 antibody
    • MPHOSPH2 antibody
    • MPM-2 reactive phosphoprotein 2 antibody
    • MPP2 antibody
    • PIG29 antibody
    • TGT3 antibody
    • Transcription factor Trident antibody
    • Trident antibody
    • WIN antibody
    • Winged-helix factor from INS-1 cells antibody
    • Winged-helix factor from INS1 cells antibody
    see all

Anti-FOXM1 antibody images

  • ab83097 at 5 µg/ml staining FOXM1 in Human spleen tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
  • Anti-FOXM1 antibody (ab83097) at 1 µg/ml + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 84 kDa
    Observed band size : 84 kDa
    Gel concentration 12%

References for Anti-FOXM1 antibody (ab83097)

This product has been referenced in:
  • Hu C  et al. LXRa-mediated downregulation of FOXM1 suppresses the proliferation of hepatocellular carcinoma cells. Oncogene N/A:N/A (2013). Read more (PubMed: 23812424) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"