Overview

  • Product name
  • Description
    Rabbit polyclonal to FOXN1
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, conjugated to KLH, corresponding to residues in Human FOXN1.

  • Positive control
    • Human Uterus tissue; Raji whole cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab113235 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 69 kDa.
IHC-P Use a concentration of 10 µg/ml.

Target

  • Function
    Transcriptional regulator involved in development.
  • Tissue specificity
    Expressed in thymus.
  • Involvement in disease
    Defects in FOXN1 are the cause of T-cell immunodeficiency congenital alopecia and nail dystrophy (TIDAND) [MIM:601705]. A disorder characterized by the association of congenital alopecia, severe T-cell immunodeficiency, and ridging and pitting of all nails.
  • Sequence similarities
    Contains 1 fork-head DNA-binding domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • FKHL20 antibody
    • Forkhead box N1 antibody
    • Forkhead box protein N1 antibody
    • FOXN 1 antibody
    • FOXN1 antibody
    • FOXN1_HUMAN antibody
    • RONU antibody
    • Rowett nude antibody
    • Transcription factor winged-helix nude antibody
    • WHN antibody
    • Winged helix nude antibody
    • Winged-helix transcription factor nude antibody
    see all

Images

  • ab113235 at 10ug/ml staining FOXN1 in Formalin-fixed, Paraffin-embedded Human Uterus tissue by Immunohistochemistry.
  • Anti-FOXN1 antibody (ab113235) at 1/1000 dilution + Raji whole cell lysate at 30 µg

    Predicted band size : 69 kDa

References

This product has been referenced in:
  • Lin Z  et al. Loss-of-function mutations in HOXC13 cause pure hair and nail ectodermal dysplasia. Am J Hum Genet 91:906-11 (2012). Read more (PubMed: 23063621) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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