Overview

  • Product name
  • Description
    Rabbit polyclonal to FOXN1
  • Tested applications
    Suitable for: Flow Cyt, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human FOXN1 aa 357-386 (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: O15353

  • Positive control
    • A549 and NCI-H460 cell line lysates; A549 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab170793 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/10 - 1/50. ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
WB 1/100 - 1/500. Predicted molecular weight: 69 kDa.

Target

  • Function
    Transcriptional regulator involved in development.
  • Tissue specificity
    Expressed in thymus.
  • Involvement in disease
    Defects in FOXN1 are the cause of T-cell immunodeficiency congenital alopecia and nail dystrophy (TIDAND) [MIM:601705]. A disorder characterized by the association of congenital alopecia, severe T-cell immunodeficiency, and ridging and pitting of all nails.
  • Sequence similarities
    Contains 1 fork-head DNA-binding domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • FKHL20 antibody
    • Forkhead box N1 antibody
    • Forkhead box protein N1 antibody
    • FOXN 1 antibody
    • FOXN1 antibody
    • FOXN1_HUMAN antibody
    • RONU antibody
    • Rowett nude antibody
    • Transcription factor winged-helix nude antibody
    • WHN antibody
    • Winged helix nude antibody
    • Winged-helix transcription factor nude antibody
    see all

Images

  • Flow cytometric analysis of A549 cells using ab170793 at a 1/10 dilution  (right/green histogram) compared to a negative control cell (left/blue histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used.

  • All lanes : Anti-FOXN1 antibody (ab170793) at 1/100 dilution

    Lane 1 : A549 cell line lysates
    Lane 2 : NCI-H460 cell line lysates

    Lysates/proteins at 35 µg per lane.


    Predicted band size : 69 kDa

References

ab170793 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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