Transcriptional regulator involved in development.
Expressed in thymus.
Involvement in disease
Defects in FOXN1 are the cause of T-cell immunodeficiency congenital alopecia and nail dystrophy (TIDAND) [MIM:601705]. A disorder characterized by the association of congenital alopecia, severe T-cell immunodeficiency, and ridging and pitting of all nails.
Flow cytometric analysis of A549 cells using ab170793 at a 1/10 dilution (right/green histogram) compared to a negative control cell (left/blue histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used.
Western blot - Anti-FOXN1 antibody (ab170793)
All lanes : Anti-FOXN1 antibody (ab170793) at 1/100 dilution
Lane 1 : A549 cell line lysates Lane 2 : NCI-H460 cell line lysates