Overview

  • Product nameAnti-FOXP3 antibody
    See all FOXP3 primary antibodies
  • Description
    Rabbit polyclonal to FOXP3
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Mouse, Human
  • Immunogen

    Three synthetic peptides derived from human FOXP3, conjugated to KLH.

  • Positive control
    • An anti thio tested on an induced culture of E. coli.

Properties

Applications

Our Abpromise guarantee covers the use of ab86006 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notesDirect ELISA: 1/40000.
    WB: 1/1000. Predicted molecular weight: 47 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionProbable transcription factor. Plays a critical role in the control of immune response.
    • Involvement in diseaseDefects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) [MIM:304790]; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy.
    • Sequence similaritiesContains 1 C2H2-type zinc finger.
      Contains 1 fork-head DNA-binding domain.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • AIID antibody
      • DIETER antibody
      • Forkhead box P3 antibody
      • Forkhead box protein P3 antibody
      • FOXP3 antibody
      • FOXP3_HUMAN antibody
      • FOXP3delta7 antibody
      • Immune dysregulation polyendocrinopathy enteropathy X linked antibody
      • Immunodeficiency polyendocrinopathy enteropathy X linked antibody
      • IPEX antibody
      • JM2 antibody
      • MGC141961 antibody
      • MGC141963 antibody
      • OTTHUMP00000025832 antibody
      • OTTHUMP00000025833 antibody
      • OTTHUMP00000226737 antibody
      • PIDX antibody
      • Scurfin antibody
      • XPID antibody
      see all

    Anti-FOXP3 antibody images

    • All lanes : Anti-FOXP3 antibody (ab86006) at 1/1000 dilution (in 5% non-fat milk-PBST solution incubated for 60 minutes)

      Lane 1 : uninduced culture of E. coli (plus anti thio at 1/5000 dilution)
      Lane 2 : induced culture of E. coli (plus anti thio at 1/5000 dilution)

      Secondary
      anti-Rabbit IgG HRP conjugate incubated for 60 minutes at 1/1000 dilution

      Predicted band size : 47 kDa
      Observed band size : 61 kDa (why is the actual band size different from the predicted?)

    References for Anti-FOXP3 antibody (ab86006)

    ab86006 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab86006.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"