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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer Preservative: 0.01% Thimerosal (merthiolate)
Constituents: Whole serum
Purity Whole antiserum
Purification notes Crude serum, final bleed
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notes Direct ELISA: 1/40000.
WB: 1/1000. Predicted molecular weight: 47 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Function Probable transcription factor. Plays a critical role in the control of immune response.
Involvement in disease Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) [MIM:304790]; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy.
Sequence similarities Contains 1 C2H2-type zinc finger. Contains 1 fork-head DNA-binding domain.
Cellular localization Nucleus.
Information by UniProt
Forkhead box P3 antibody
Anti-FOXP3 antibody images
Western blot - FOXP3 antibody (ab86006)
All lanes : Anti-FOXP3 antibody (ab86006) at 1/1000 dilution (in 5% non-fat milk-PBST solution incubated for 60 minutes) Lane 1 : uninduced culture of E. coli (plus anti thio at 1/5000 dilution) Lane 2 : induced culture of E. coli (plus anti thio at 1/5000 dilution) Secondary anti-Rabbit IgG HRP conjugate incubated for 60 minutes at 1/1000 dilution
Predicted band size : 47 kDa Observed band size : 61 kDa ( why is the actual band size different from the predicted?)
References for Anti-FOXP3 antibody (ab86006)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"