Overview

  • Product name
  • Description
    Rabbit polyclonal to FOXRED2
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence, corresponding to amino acids 34-170 of Human FOXRED2.

  • Positive control
    • Human hippocampus tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab122182 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration.
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation.
  • Sequence similarities
    Belongs to the FOXRED2 family.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localization
    Endoplasmic reticulum lumen.
  • Information by UniProt
  • Database links
  • Alternative names
    • D15Bwg0759e antibody
    • Endoplasmic reticulum flavoprotein associated with degradation antibody
    • ERFAD antibody
    • FAD dependent oxidoreductase domain containing 2 antibody
    • FAD-dependent oxidoreductase domain-containing protein 2 antibody
    • FLJ23322 antibody
    • foxred2 antibody
    • FXRD2_HUMAN antibody
    • RP5-1119A7.4 antibody
    see all

Images

  • ab122182 at 1/25 dilution staining FOXRED2 in Paraffin-embedded Human hippocampus tissue by Immunohistochemistry.
  • All lanes : Anti-FOXRED2 antibody (ab122182) at 1/250 dilution

    Lane 1 : Negative control (vector only transfected HEK293T lysate)
    Lane 2 : FOXRED2 over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells

References

ab122182 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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