Anti-FPR1 antibody - Extracellular domain (ab150533)

Overview

  • Product name
    Anti-FPR1 antibody - Extracellular domain
    See all FPR1 primary antibodies
  • Description
    Rabbit polyclonal to FPR1 - Extracellular domain
  • Specificity
    BLAST analysis of the peptide immunogen showed no homology with other human proteins.
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to 16 amino acids from the 2nd extracellular domain of Human FPR1 (NP_002020.1).

  • Positive control
    • Human tonsil tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab150533 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 2 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
  • Tissue specificity
    Neutrophils.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications
    Phosphorylated; which is necessary for desensitization.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • fMet Leu Phe receptor antibody
    • fMet-Leu-Phe receptor antibody
    • FMLP antibody
    • fMLP receptor antibody
    • FMLPR antibody
    • Formyl peptide receptor 1 antibody
    • FPR 1 antibody
    • FPR antibody
    • FPR receptor antibody
    • FPR1 antibody
    • FPR1_HUMAN antibody
    • N formyl peptide chemoattractant receptor antibody
    • N formyl peptide receptor antibody
    • N formylpeptide chemoattractant receptor antibody
    • N-formyl peptide receptor antibody
    • N-formylpeptide chemoattractant receptor antibody
    see all

Images

  • Immunohistochemical analysis of formalin fixed, paraffin embedded Human tonsil tissue labeling FPR1 with ab150533 at 2 µg/ml .

References

This product has been referenced in:

See 1 Publication for this product

Customer reviews and Q&As

Application
Flow Cytometry
Fixation
Paraformaldehyde
Sample
Mouse Cell (primary circulating leukocytes)
Specification
primary circulating leukocytes
Gating Strategy
CD45.2+, Ly6G+
Permeabilization
No
Username

Dr. Ricky Besla

Verified customer

Submitted Jan 26 2015

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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