FunctionIFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication.
Sequence similaritiesBelongs to the CD225 family.
Post-translational modificationsPalmitoylation on membrane-proximal cysteines controls clustering in membrane compartments and antiviral activity against influenza virus.
Immunofluorescent staining of MCF-7 cells, using ab74699 at a 1/500 dilution, minus immunising peptide (left image) and plus immunising peptide (right image).
References for Anti-Fragilis antibody (ab74699)
This product has been referenced in:
Bhartiya D et al. Very Small Embryonic- like Stem Cells with Maximum Regenerative Potential get Discarded during Cord Blood Banking and Bone Marrow Processing for Autologous Stem Cell Therapy. Stem Cells Dev : (2011).
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