ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
Application notesIs unsuitable for IHC-P.
RelevanceThe protein encoded by the FRAT1 gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and also positively regulates the Wnt signaling pathway. It may play a role in tumor progression and in lymphomagenesis.
frequently rearranged in advanced T cell lymphomas antibody
Frequently rearranged in advanced T-cell lymphomas antibody
GSK 3 binding protein FRAT1 antibody
proto oncogene FRAT1 antibody
Anti-FRAT1 antibody [EPR3900] images
Western blot - FRAT1 antibody [EPR3900] (ab108405)
All lanes : Anti-FRAT1 antibody [EPR3900] (ab108405) at 1/1000 dilution
Lane 1 : HeLa cell lysate Lane 2 : MCF7 cell lysate
Lysates/proteins at 10 µg per lane.
Predicted band size : 29 kDa
References for Anti-FRAT1 antibody [EPR3900] (ab108405)
This product has been referenced in:
Zhang W et al. Frequently rearranged in advanced T-cell lymphomas-1 demonstrates oncogenic properties in prostate cancer. Mol Med Rep14:3551-8 (2016).
Read more (PubMed: 27599661) »
Jin R et al. The metastasis suppressor NDRG1 modulates the phosphorylation and nuclear translocation of ß-catenin through mechanisms involving FRAT1 and PAK4. J Cell Sci127:3116-30 (2014).
Read more (PubMed: 24829151) »