Anti-FRK antibody [4E1] (ab91623)

Overview

  • Product nameAnti-FRK antibody [4E1]
    See all FRK primary antibodies
  • Description
    Mouse monoclonal [4E1] to FRK
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Purified recombinant fragment of Human FRK expressed in E. Coli.

  • Positive control
    • K562 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab91623 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notesELISA: 1/10000.
    WB: 1/500 - 1/2000. Predicted molecular weight: 58 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionPositively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation possibly by reducing its binding to NEDD4. May function as a tumor suppressor.
    • Tissue specificityRestricted to cells lines derived from tissues of lymphoid, brain, breast, colon and bladder origin.
    • Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
      Contains 1 protein kinase domain.
      Contains 1 SH2 domain.
      Contains 1 SH3 domain.
    • Cellular localizationCytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • Beta cell Src homology tyrosine kinase antibody
      • BSK antibody
      • BSK/IYK antibody
      • C85044 antibody
      • Frk antibody
      • Frk fyn related kinase antibody
      • FRK_HUMAN antibody
      • FYN related kinase antibody
      • FYN-related kinase antibody
      • GASK antibody
      • Gastrointestinal associated kinase antibody
      • Gastrointestinal associated tyrosine kinase antibody
      • GTK antibody
      • GTK, mouse, homolog of antibody
      • Intestine tyrosine kinase antibody
      • Nuclear tyrosine protein kinase RAK antibody
      • Protein-tyrosine kinase 5 antibody
      • PTK5 antibody
      • PTK5 protein tyrosine kinase 5 antibody
      • RAK antibody
      • Tyrosine protein kinase FRK antibody
      • Tyrosine-protein kinase FRK antibody
      see all

    Anti-FRK antibody [4E1] images

    • Anti-FRK antibody [4E1] (ab91623) at 1/500 dilution + K562 cell lysate

      Predicted band size : 58 kDa

    References for Anti-FRK antibody [4E1] (ab91623)

    ab91623 has not yet been referenced specifically in any publications.

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