Overview

  • Product name
  • Description
    Rabbit polyclonal to FRK
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 36-85 (CSPQSQRHGH YFVALFDYQA RTAEDLSFRA GDKLQVLDTL HEGWWFARHL) of Human FRK (NP_002022).

  • Positive control
    • Transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab87201 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 58 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation possibly by reducing its binding to NEDD4. May function as a tumor suppressor.
  • Tissue specificity
    Restricted to cells lines derived from tissues of lymphoid, brain, breast, colon and bladder origin.
  • Sequence similarities
    Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
    Contains 1 protein kinase domain.
    Contains 1 SH2 domain.
    Contains 1 SH3 domain.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Beta cell Src homology tyrosine kinase antibody
    • BSK antibody
    • BSK/IYK antibody
    • C85044 antibody
    • Frk antibody
    • Frk fyn related kinase antibody
    • FRK_HUMAN antibody
    • FYN related kinase antibody
    • FYN-related kinase antibody
    • GASK antibody
    • Gastrointestinal associated kinase antibody
    • Gastrointestinal associated tyrosine kinase antibody
    • GTK antibody
    • GTK, mouse, homolog of antibody
    • Intestine tyrosine kinase antibody
    • Nuclear tyrosine protein kinase RAK antibody
    • Protein-tyrosine kinase 5 antibody
    • PTK5 antibody
    • PTK5 protein tyrosine kinase 5 antibody
    • RAK antibody
    • Tyrosine protein kinase FRK antibody
    • Tyrosine-protein kinase FRK antibody
    see all

Images

  • Anti-FRK antibody (ab87201) at 1 µg/ml (in 5% skim milk / PBS buffer) + Transfected 293T cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 58 kDa
    Observed band size : 58 kDa

References

ab87201 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab87201.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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