Recombinant
RabMAb

Anti-Fructose 6 Phosphate Kinase antibody [EPR10735] (ab170868)

Overview

  • Product name
    Anti-Fructose 6 Phosphate Kinase antibody [EPR10735]
    See all Fructose 6 Phosphate Kinase primary antibodies
  • Description
    Rabbit monoclonal [EPR10735] to Fructose 6 Phosphate Kinase
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ICC/IFmore details
    Unsuitable for: Flow Cyt,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human Fructose 6 Phosphate Kinase (Cysteine residue). The exact sequence is proprietary.
    Database link: P08237
    (Peptide available as ab207506)

  • Positive control
    • HeLa cells; Human skeletal muscle, HeLa, Mouse muscle and Rat muscle lysates.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab170868 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 85 kDa.
ICC/IF 1/100 - 1/250.
  • Application notes
    Is unsuitable for Flow Cyt,IHC-P or IP.
  • Target

    • Pathway
      Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.
    • Involvement in disease
      Defects in PFKM are the cause of glycogen storage disease type 7 (GSD7) [MIM:232800]; also known as Tarui disease. GSD7 is an autosomal recessive disorder characterized by exercise intolerance with associated nausea and vomiting. Short bursts of intense activity are particularly difficult. Severe muscle cramps and myoglobinuria develop after vigorous exercise. Most patients obtain a "second wind" when the onset of exercise is followed by a brief rest period. In time patients adjust their activity level and are well compensated.
    • Sequence similarities
      Belongs to the phosphofructokinase family. Two domains subfamily.
    • Information by UniProt
    • Database links
    • Alternative names
      • 6 Phosphofructokinase Muscle Type antibody
      • 6-phosphofructokinase antibody
      • 6-phosphofructokinase muscle type antibody
      • EC 2.7.1.1 antibody
      • EC 2.7.1.11 antibody
      • GSD7 antibody
      • K6PF_HUMAN antibody
      • MGC8699 antibody
      • muscle type antibody
      • PFK, muscle type antibody
      • PFK-A antibody
      • PFKA antibody
      • PFKL antibody
      • PFKM antibody
      • PFKP antibody
      • PFKX antibody
      • Phosphofructo 1 Kinase Isozyme A antibody
      • Phosphofructo-1-kinase isozyme A antibody
      • Phosphofructokinase 1 antibody
      • Phosphofructokinase M antibody
      • Phosphofructokinase, muscle antibody
      • Phosphofructokinase, muscle type antibody
      • Phosphofructokinase, polypeptide X antibody
      • Phosphofructokinase-M antibody
      • Phosphohexokinase antibody
      see all

    Images

    • Immunofluorescent analysis of HeLa cells labeling Fructose 6 Phosphate Kinase with ab170868 at 1/100 dilution (green). DAPI nuclear staining (blue).

    • All lanes : Anti-Fructose 6 Phosphate Kinase antibody [EPR10735] (ab170868) at 1/1000 dilution

      Lane 1 : Human skeletal muscle lysate
      Lane 2 : HeLa lysate
      Lane 3 : Mouse muscle lysate
      Lane 4 : Rat muscle lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 85 kDa

    References

    ab170868 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab170868.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up