Overview

  • Product nameAnti-FRZB antibody
    See all FRZB primary antibodies
  • Description
    Mouse monoclonal to FRZB
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant full length protein: HEPIKPCKSV CERARQGCEP ILIKYRHSWP ENLACEELPV YDRGVCISPE AIVTADGADF PMDSSNGNCR GASSERCKCK PIRATQKTY, corresponding to amino acids 102-190 of Human FRZB

Properties

Applications

Our Abpromise guarantee covers the use of ab55026 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

Target

  • RelevanceSFRP3/FRZB appears to be involved in limb skeletogenesis by regulating chondrocyte maturation and long bone development. Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. Antagonist of Wnt8 signaling.
  • Cellular localizationSecreted
  • Database links
  • Alternative names
    • FIZ antibody
    • FRE antibody
    • Frezzled antibody
    • Fritz antibody
    • Frizzled-related protein 1 antibody
    • FRP antibody
    • FrzB 1 antibody
    • FRZB antibody
    • FRZB1 antibody
    • OTTMUSP00000014350 antibody
    • RP23-33L19.1 antibody
    • Secreted frizzled related protein 3 [Precursor] antibody
    • Secreted frizzled related sequence protein 3 antibody
    • sFRP 3 antibody
    • SFRP antibody
    see all

Anti-FRZB antibody images

  • Western blot against tagged recombinant protein immunogen using ab55026 FRZB antibody at 1ug/ml. Predicted band size of immunogen is 36 kDa.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

References for Anti-FRZB antibody (ab55026)

This product has been referenced in:
  • Khare V  et al. Mesalamine modulates intercellular adhesion through inhibition of p-21 activated kinase-1. Biochem Pharmacol 85:234-44 (2013). WB ; Human . Read more (PubMed: 23146664) »

See 1 Publication for this product

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Western blot
Sample Human Cell lysate - other (HT29, HCT116 colon cancer cells)
Loading amount 50 µg
Specification HT29, HCT116 colon cancer cells
Treatment FRZB-stimulated drugs
Gel Running Conditions Reduced Denaturing (4-12% PAGE)
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: RT°C
Username

Dr. Alex Lyakhovich

Verified customer

Submitted Apr 17 2009

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"