Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-KVQDIKAREKDGKGR
    • Amino acids
      296 to 310

Associated products

Specifications

Our Abpromise guarantee covers the use of ab45845 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-FSD1 antibody (ab42691)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

General Info

  • Alternative names
    • Fibronectin type 3 and SPRY (spla, ryanodine) domain containing (with coiled-coil motif) 1
    • Fibronectin type 3 and SPRY domain containing 1
    • Fibronectin type III and SPRY domain containing 1
    • Fibronectin type III and SPRY domain-containing protein 1
    • Fibronectin type III and SPRY domains containing protein 1
    • FSD1
    • FSD1_HUMAN
    • GLFND
    • MGC3213
    • MGC58341
    • Microtubule-associated protein GLFND
    • MID1-related protein 1
    • midline 1-related protein 1
    • MIR1
    • VLP27
    see all
  • Function
    May be involved in microtubule organization and stabilization.
  • Tissue specificity
    Highly expressed in brain tissues, including cerebellum, cerebral cortex, medulla, occipital pole, frontal lobe, temporal lobe and putamen. Lower expression in spinal chord.
  • Sequence similarities
    Contains 1 B30.2/SPRY domain.
    Contains 1 COS domain.
    Contains 1 fibronectin type-III domain.
  • Domain
    B30.2 box contains a microtubule-binding site.
  • Cellular localization
    Cytoplasm > cytoskeleton > centrosome. Nucleus. Cytoplasm. Cleavage furrow. Cell-cycle-dependent association with the centrosome. Colocalizes with a subpopulation of microtubules. Does not associates with microtubules during mitosis but reassociates with microtubules during cytokinesis. Localizes to the central portions of a small subset of microtubules in interphase cells and a subpopulation of microtubules in the cleavage furrow, not present in the mitotic spindle.
  • Information by UniProt

References

ab45845 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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