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Amino Acid Sequence
Amino acids 296 to 310 Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-FSD1 antibody (
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Fibronectin type 3 and SPRY (spla, ryanodine) domain containing (with coiled-coil motif) 1
Fibronectin type 3 and SPRY domain containing 1
Fibronectin type III and SPRY domain containing 1
Function May be involved in microtubule organization and stabilization.
Tissue specificity Highly expressed in brain tissues, including cerebellum, cerebral cortex, medulla, occipital pole, frontal lobe, temporal lobe and putamen. Lower expression in spinal chord.
Sequence similarities Contains 1 B30.2/SPRY domain. Contains 1 COS domain. Contains 1 fibronectin type-III domain.
Domain B30.2 box contains a microtubule-binding site.
Cellular localization Cytoplasm > cytoskeleton > centrosome. Nucleus. Cytoplasm. Cleavage furrow. Cell-cycle-dependent association with the centrosome. Colocalizes with a subpopulation of microtubules. Does not associates with microtubules during mitosis but reassociates with microtubules during cytokinesis. Localizes to the central portions of a small subset of microtubules in interphase cells and a subpopulation of microtubules in the cleavage furrow, not present in the mitotic spindle.
Information by UniProt
References for FSD1 peptide (296-310) (ab45845)
has not yet been referenced specifically in any publications.
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