Anti-FSH antibody (ab8746)
Key features and details
- Rabbit polyclonal to FSH
- Suitable for: IHC-FoFr
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-FSH antibody
See all FSH primary antibodies -
Description
Rabbit polyclonal to FSH -
Host species
Rabbit -
Specificity
This antibody reacts with the 35 kD beta follicle stimulating hormone which, in females, is involved in maturation of ovarian follicles and estrogen secretion, and in males stimulates secretion of testosterone. This antibody reacts with FSH producing cells in the anterior pituitary. -
Tested applications
Suitable for: IHC-FoFrmore details -
Species reactivity
Reacts with: Human -
Immunogen
Full length native protein (purified) corresponding to Human FSH.
-
Positive control
- Pituitary carcinoma.
-
General notes
Prolonged fixation in buffered formalin can destroy the epitopeThe Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.1% Sodium azide
Constituent: 0.01% PBS -
Concentration information loading...
-
Purity
Protein G purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab8746 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-FoFr |
Use at an assay dependent concentration.
|
Notes |
---|
IHC-FoFr
Use at an assay dependent concentration. |
Target
-
Relevance
Follicle stimulating hormone enables ovarian folliculogenesis to the antral follicle stage and is essential for Sertoli cell proliferation and maintenance of sperm quality in the testis. Members of the pituitary glycoprotein hormone family, of which FSH is one (see also luteinizing hormone, chorionic gonadotropin, and thyroid stimulating hormone), consist of a shared alpha chain and a beta chain encoded by a separate gene. The FSHB gene encodes the beta subunit of follicle stimulating hormone. -
Cellular localization
Secreted -
Database links
- Entrez Gene: 1081 Human
- Entrez Gene: 2488 Human
- Omim: 118850 Human
- Omim: 136530 Human
- SwissProt: P01215 Human
- SwissProt: P01225 Human
-
Alternative names
- Anterior pituitary glycoprotein hormones common subunit alpha antibody
- CG alpha antibody
- CGA antibody
see all
Datasheets and documents
-
SDS download
-
Datasheet download
References (1)
ab8746 has been referenced in 1 publication.
- Mathioudakis N et al. Expression of the pituitary stem/progenitor marker GFRa2 in human pituitary adenomas and normal pituitary. Pituitary 18:31-41 (2015). PubMed: 24402129