Overview

  • Product nameAnti-FTS antibody
    See all FTS primary antibodies
  • Description
    Mouse monoclonal to FTS
  • Tested applicationsSuitable for: ICC/IF, IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-293 of Human FTS

Properties

Applications

Our Abpromise guarantee covers the use of ab56407 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration. PubMed: 21424602
IHC-P Use at an assay dependent concentration. PubMed: 21424602
WB Use a concentration of 1 - 5 µg/ml.

Target

  • FunctionComponent of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade.
  • Sequence similaritiesBelongs to the ubiquitin-conjugating enzyme family. FTS subfamily.
  • Cellular localizationCytoplasm. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • AKT interacting protein antibody
    • AKT-interacting protein antibody
    • AKTIP antibody
    • AKTIP_HUMAN antibody
    • FT 1 antibody
    • FT1 antibody
    • Fused toes homolog antibody
    • Fused toes protein homolog antibody
    see all

Anti-FTS antibody images

  • Western blot against tagged recombinant protein immunogen using ab56407 FTS antibody at 1ug/ml. Predicted band size of immunogen is 58 kDa

References for Anti-FTS antibody (ab56407)

This product has been referenced in:
  • Anandharaj A  et al. Fused Toes Homolog modulates radiation cytotoxicity in uterine cervical cancer cells. Mol Biol Rep 38:5361-70 (2011). ICC/IF, IHC-P ; Human . Read more (PubMed: 21424602) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"