Overview

  • Product nameAnti-FTSJD2 antibody
    See all FTSJD2 primary antibodies
  • Description
    Rabbit polyclonal to FTSJD2
  • Tested applicationsSuitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    A region between residue 800 and the C-terminus (residue 835) of human FTSJD2

  • Positive control
    • Whole cell lysate from 293T cells transfected with a myc-FTSJD2 expression construct. Whole cell lysate from 293T cells. Whole cell lysate from G361 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab70388 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IP
  • Application notesIP: Use at 1 - 5 µg/mg of lysate.
    WB: 1/5000 - 1/25000. Detects a band of approximately 100 kDa (predicted molecular weight: 96 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionS-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.
    • Sequence similaritiesContains 1 G-patch domain.
      Contains 1 RrmJ-type SAM-dependent 2'-O-MTase domain.
      Contains 1 WW domain.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • Cap methyltransferase 1 antibody
      • Cap-specific mRNA (nucleoside-2''-O-)-methyltransferase 1 antibody
      • Cap1 2''O-ribose methyltransferase 1 antibody
      • CMTR1 antibody
      • CMTR1_HUMAN antibody
      • FLJ22156 antibody
      • FtsJ methyltransferase domain containing 2 antibody
      • FtsJ methyltransferase domain-containing protein 2 antibody
      • FTSJD 2 antibody
      • hMTr1 antibody
      • Interferon-stimulated gene 95 kDa protein antibody
      • ISG95 antibody
      • KIAA0082 antibody
      • MTr1 antibody
      • OTTHUMP00000016324 antibody
      • Uncharacterized protein KIAA0082 antibody
      see all

    Anti-FTSJD2 antibody images

    • All lanes : Anti-FTSJD2 antibody (ab70388) at 0.1 µg/ml

      Lane 1 : Whole cell lysate from 293T cells transfected with a myc-FTSJD2 expression construct at 15 µg
      Lane 2 : Whole cell lysate from 293T cells that were mock transfected at 60 µg
      Lane 3 : Whole cell lysate from G361 cells at 15 µg


      Predicted band size : 96 kDa
      Observed band size : 100 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 50 kDa,60 kDa. We are unsure as to the identity of these extra bands.

    References for Anti-FTSJD2 antibody (ab70388)

    ab70388 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"