Overview

  • Product nameAnti-FUCA1 antibody
    See all FUCA1 primary antibodies
  • Description
    Mouse monoclonal to FUCA1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 23-462 of Human FUCA1

Properties

Applications

Our Abpromise guarantee covers the use of ab55000 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionAlpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
    • Involvement in diseaseDefects in FUCA1 are the cause of fucosidosis (FUCA1D) [MIM:230000]. FUCA1D is an autosomal recessive lysosomal storage disease characterized by accumulation of fucose-containing glycolipids and glycoproteins in various tissues. Clinical signs include facial dysmorphism, dysostosis multiplex, moderate hepatomegaly, severe intellectual deficit, deafness, and according to age, angiokeratomas.
    • Sequence similaritiesBelongs to the glycosyl hydrolase 29 family.
    • Cellular localizationLysosome.
    • Information by UniProt
    • Database links
    • Alternative names
      • Alpha L fucosidase I antibody
      • Alpha L fucoside fucohydrolase antibody
      • Alpha-L-fucosidase 1 antibody
      • Alpha-L-fucosidase I antibody
      • Alpha-L-fucoside fucohydrolase 1 antibody
      • FUCA antibody
      • FUCA1 antibody
      • FUCO_HUMAN antibody
      • fucosidase, alpha-L, tissue antibody
      • fucosidase, alpha-L- 1, tissue antibody
      • Tissue alpha L fucosidase antibody
      • Tissue alpha-L-fucosidase antibody
      see all

    Anti-FUCA1 antibody images



    • Predicted band size : 53 kDa
      FUCA1 antibody (ab55000) at 1ug/lane + K-562 cell lysate at 25ug/lane.

    References for Anti-FUCA1 antibody (ab55000)

    This product has been referenced in:
    • Otero-Estévez O  et al. Decreased expression of alpha-L-fucosidase gene FUCA1 in human colorectal tumors. Int J Mol Sci 14:16986-98 (2013). WB ; Human . Read more (PubMed: 23965968) »

    See 1 Publication for this product

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