Overview

  • Product name
    Anti-Fucose mutarotase antibody
    See all Fucose mutarotase primary antibodies
  • Description
    Rabbit polyclonal to Fucose mutarotase
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: MVALKGVPAL LSPELLYALA RMGHGDEIVL ADLNFPASSI CQCGPMEIRA DGLGIPQLLE AVL, corresponding to amino acids 1-63 of Human Fucose mutarotase.

  • Positive control
    • Human kidney tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab122543 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Perform heat mediated antigen retrieval at pH6 before commencing with IHC staining protocol.

Target

  • Function
    Involved in the interconversion between alpha- and beta-L-fucoses. L-Fucose (6-deoxy-L-galactose) exists as alpha-L-fucose (29.5%) and beta-L-fucose (70.5%), the beta-form is metabolized through the salvage pathway. GDP-L-fucose formed either by the de novo or salvage pathways is transported into the endoplasmic reticulum, where it serves as a substrate for N- and O-glycosylations by fucosyltransferases. Fucosylated structures expressed on cell surfaces or secreted in biological fluids are believed to play a critical role in cell-cell adhesion and recognition processes.
  • Sequence similarities
    Belongs to the rbsD / fucU family.
  • Information by UniProt
  • Database links
  • Alternative names
    • C10orf125 antibody
    • Chromosome 10 open reading frame 125 antibody
    • FUCM_HUMAN antibody
    • Fucose mutarotase antibody
    • FUCU antibody
    • FUOM antibody
    • Protein fucU homolog antibody
    see all

Images

  • ab122543, at 1/125 dilution, staining Fucose mutarotase in paraffin-embedded Human kidney tissue by Immunohistochemistry, showing strong cytoplasmic positivity in cells in tubules.

References

ab122543 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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