Anti-Fumarylacetoacetate hydrolase antibody [2] (ab83078)

Overview

  • Product nameAnti-Fumarylacetoacetate hydrolase antibody [2]
    See all Fumarylacetoacetate hydrolase primary antibodies
  • Description
    Mouse monoclonal [2] to Fumarylacetoacetate hydrolase
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length Human Fumarylacetoacetate hydrolase protein expressed in E. coli.

  • Positive control
    • HEK293 whole cell lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab83078 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 46 kDa.
ELISA Use at an assay dependent dilution.

Target

  • RelevanceFumarylacetoacetate hydrolase is the last enzyme in the tyrosine catabolism pathway. FAH deficiency is associated with Type 1 hereditary tyrosinemia (HT). This is an autosomal recessive inborn error of metabolism that occurs in both an acute and a chronic form. Clinical characteristics of the acute form include hepatic failure and death in infancy, whereas children with the chronic form have renal tubular dysfunction and hypophosphatemic rickets, progressive liver disease with development of hepatocellular carcinoma. Dietary treatment with restriction of tyrosine and phenylalanine alleviates the rickets, but liver transplantation has so far been the only definite treatment.
  • Database links
  • Alternative names
    • Beta diketonase antibody
    • FAA antibody
    • FAH antibody
    • Fumarylacetoacetase antibody
    • Fumarylacetoacetate antibody
    • Fumarylacetoacetate hydrolase antibody
    see all

Anti-Fumarylacetoacetate hydrolase antibody [2] images

  • Anti-Fumarylacetoacetate hydrolase antibody [2] (ab83078) at 1/500 dilution + Whole cell lysates prepared from HEK293 cells.

    Predicted band size : 46 kDa

References for Anti-Fumarylacetoacetate hydrolase antibody [2] (ab83078)

ab83078 has not yet been referenced specifically in any publications.

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