Overview

  • Product nameAnti-FVT1 antibody
    See all FVT1 primary antibodies
  • Description
    Mouse monoclonal to FVT1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-333 of Human FVT1

Properties

Applications

Our Abpromise guarantee covers the use of ab58122 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCatalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
    • Tissue specificityExpressed in all tissues examined. Highest expression in placenta. High expression in lung, kidney, stomach and small intestine, low expression in heart, spleen and skeletal muscle. Weakly expressed in normal hematopoietic tissues. Higher expression in some T-cell malignancies and PHA-stimulated lymphocytes.
    • PathwayLipid metabolism; sphingolipid metabolism.
    • Involvement in diseaseA chromosomal aberration involving KDSR is a cause of follicular lymphoma; also known as type II chronic lymphatic leukemia. Translocation t(2;18)(p11;q21) with a Ig J kappa chain region (PubMed:8417785).
    • Sequence similaritiesBelongs to the short-chain dehydrogenases/reductases (SDR) family.
    • Cellular localizationEndoplasmic reticulum membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • 3 dehydrosphinganine reductase antibody
      • 3 ketodihydrosphingosine reductase antibody
      • 3-dehydrosphinganine reductase antibody
      • 3-ketodihydrosphingosine reductase antibody
      • DHSR antibody
      • FLJ36555 antibody
      • FLJ92680 antibody
      • Follicular lymphoma variant translocation 1 antibody
      • Follicular variant translocation protein 1 antibody
      • FVT 1 antibody
      • FVT-1 antibody
      • FVT1 antibody
      • KDS reductase antibody
      • KDSR antibody
      • KDSR_HUMAN antibody
      • SDR35C1 antibody
      • Short chain dehydrogenase/reductase family 35C member 1 antibody
      see all

    Anti-FVT1 antibody images



    • Predicted band size : 36 kDa
      FVT1 antibody (ab58122) at 1ug/lane + Jurkat cell lysate at 25ug/lane.

    References for Anti-FVT1 antibody (ab58122)

    ab58122 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab58122.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"