Overview

  • Product nameAnti-FXR1 antibody
    See all FXR1 primary antibodies
  • Description
    Mouse monoclonal to FXR1
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: VKKNTFFKCT VDVPEDLREA CANENAHKDF KKAVGACRIF YHPETTQLMI LSASEATVKR VNILSDMHLR SIRTKLMLMS RNEEATKHLE CTKQLAAAFH , corresponding to amino acids 121-220 of Human FXR1

Properties

Applications

Our Abpromise guarantee covers the use of ab56386 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionRNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs.
    • Tissue specificityExpressed in all tissues examined including heart, brain, kidney and testis.
    • Sequence similaritiesBelongs to the FMR1 family.
      Contains 2 KH domains.
    • Post-translational
      modifications
      Arg-445 is dimethylated, probably to asymmetric dimethylarginine.
    • Cellular localizationCytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • Fragile X mental retardation autosomal homolog 1 antibody
      • Fragile X mental retardation syndrome related protein 1 antibody
      • Fragile X mental retardation syndrome-related protein 1 antibody
      • FXR1 antibody
      • FXR1_HUMAN antibody
      • FXR1P antibody
      • hFXR1p antibody
      see all

    Anti-FXR1 antibody images

    • FXR1 antibody (ab56386) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human colon adenocarcinoma.
    • Western blot against tagged recombinant protein immunogen using ab56386 FXR1 antibody at 1ug/ml. Predicted band size of immunogen is 34 kDa

    References for Anti-FXR1 antibody (ab56386)

    This product has been referenced in:
    • Oldenburg AR  et al. Deregulation of Fragile X-related protein 1 by the lipodystrophic lamin A p.R482W mutation elicits a myogenic gene expression program in preadipocytes. Hum Mol Genet N/A:N/A (2013). WB ; Human . Read more (PubMed: 24108105) »

    See 1 Publication for this product

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    There are currently no Abreviews or Questions for ab56386.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"