Anti-FXYD1 antibody [41AT858.235] (ab38685)

Overview

  • Product nameAnti-FXYD1 antibody [41AT858.235]
    See all FXYD1 primary antibodies
  • Description
    Mouse monoclonal [41AT858.235] to FXYD1
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S68 of mouse PLM.

Properties

Applications

Our Abpromise guarantee covers the use of ab38685 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/100 - 1/500. Predicted molecular weight: 10 kDa.

Target

  • RelevancePLM (FXYD1)is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. PLM may be phosphorylated by several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity.
  • Cellular localizationMembrane; single-pass type I membrane protein
  • Database links
  • Alternative names
    • FXYD domain containing ion transport regulator 1 antibody
    • Phospholemman antibody
    • PLM antibody

Anti-FXYD1 antibody [41AT858.235] images

  • Anti-FXYD1 antibody [41AT858.235] (ab38685) at 1/100 dilution + 293 cells transfected with a plasmid encoding PLM.

    Predicted band size : 10 kDa

References for Anti-FXYD1 antibody [41AT858.235] (ab38685)

ab38685 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Sample Rabbit Cell lysate - whole cell (cardiac myocytes)
Loading amount 20 µg
Specification cardiac myocytes
Gel Running Conditions Non-reduced Denaturing
Blocking step Milk as blocking agent for 30 minute(s) · Concentration: 1% · Temperature: 25°C
Username

Abcam user community

Verified customer

Submitted Sep 21 2007

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"