Overview

  • Product nameAnti-FYB antibody
    See all FYB primary antibodies
  • Description
    Rabbit polyclonal to FYB
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 382-658 of Human FYB (NP_955367).

  • Positive control
    • 293T, Jurkat and Raji whole cell lysates.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferpH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab111611 is purified by antigen-affinity chromatography.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab111611 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 85 kDa.

Target

  • FunctionActs as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2.
  • Tissue specificityExpressed in hematopoietic tissues such as myeloid and T-cells, spleen and thymus. Not expressed in B-cells, nor in non-lymphoid tissues.
  • Sequence similaritiesContains 1 SH3 domain.
  • Post-translational
    modifications
    T-cell receptor ligation leads to increased tyrosine phosphorylation.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • ADAP antibody
    • Adhesion and degranulation promoting adaptor protein antibody
    • FYB 120/130 antibody
    • Fyb antibody
    • FYB-120/130 antibody
    • FYB_HUMAN antibody
    • FYN binding protein antibody
    • FYN T binding protein antibody
    • FYN-binding protein antibody
    • FYN-T-binding protein antibody
    • p120/p130 antibody
    • PRO0823 antibody
    • SLAP 130 antibody
    • SLAP-130 antibody
    • SLAP130 antibody
    • SLP 76 associated phosphoprotein antibody
    • SLP-76-associated phosphoprotein antibody
    • SLP76 associated phosphoprotein antibody
    see all

Anti-FYB antibody images

  • Anti-FYB antibody (ab111611) at 1/1000 dilution + Raji whole cell lysate at 30 µg

    Predicted band size : 85 kDa

References for Anti-FYB antibody (ab111611)

ab111611 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"