Overview

  • Product nameAnti-FYB antibody
    See all FYB primary antibodies
  • Description
    Rabbit polyclonal to FYB
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Dog
  • Immunogen

    Synthetic peptide, corresponding to a region within C terminal amino acids 692-741 (MGDEVYDDVD TSDFPVSSAE MSQGTNVGKA KTEEKDLKKL KKQEKEEKDF) of Human FYB (NP_955367).

  • Positive control
    • A549 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab125455 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 91 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionActs as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2.
  • Tissue specificityExpressed in hematopoietic tissues such as myeloid and T-cells, spleen and thymus. Not expressed in B-cells, nor in non-lymphoid tissues.
  • Sequence similaritiesContains 1 SH3 domain.
  • Post-translational
    modifications
    T-cell receptor ligation leads to increased tyrosine phosphorylation.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • ADAP antibody
    • Adhesion and degranulation promoting adaptor protein antibody
    • FYB 120/130 antibody
    • Fyb antibody
    • FYB-120/130 antibody
    • FYB_HUMAN antibody
    • FYN binding protein antibody
    • FYN T binding protein antibody
    • FYN-binding protein antibody
    • FYN-T-binding protein antibody
    • p120/p130 antibody
    • PRO0823 antibody
    • SLAP 130 antibody
    • SLAP-130 antibody
    • SLAP130 antibody
    • SLP 76 associated phosphoprotein antibody
    • SLP-76-associated phosphoprotein antibody
    • SLP76 associated phosphoprotein antibody
    see all

Anti-FYB antibody images

  • Anti-FYB antibody (ab125455) at 1 µg/ml + A549 cell lysate at 10 µg

    Secondary
    Goat anti-Rabbit IgG-HRP

    Predicted band size : 91 kDa

References for Anti-FYB antibody (ab125455)

ab125455 has not yet been referenced specifically in any publications.

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