Anti-G protein alpha S antibody (ab101736)

Overview

  • Product nameAnti-G protein alpha S antibody
    See all G protein alpha S primary antibodies
  • Description
    Goat polyclonal to G protein alpha S
  • Specificityab101736 is expected to recognize all three reported isoforms NP_000507.1, NP_001070956.1 and NP_536350.2.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Cow, Dog, Pig
  • Immunogen

    Synthetic peptide:

    C-QAARSNSDGEKATK

    , corresponding to internal sequence amino acids 78-91 of Human G protein alpha S (NP_000507.1).

  • Positive control
    • Jurkat cell line lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab101736 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 46 kDa).

Target

  • RelevanceGuanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Alternative splicing of downstream exons of the GNAS gene is observed, which results in different forms of the stimulatory G protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants have been found for this gene, but the full-length nature and/or biological validity of some variants have not been determined. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.
  • Cellular localizationCell Membrane
  • Database links
  • Alternative names
    • Adenylate cyclase stimulating G alpha protein antibody
    • AHO antibody
    • Alternative gene product encoded by XL exon antibody
    • C20orf45 antibody
    • dJ309F20.1.1 antibody
    • dJ806M20.3.3 antibody
    • Extra large alphas protein antibody
    • GNAS antibody
    • GNAS complex locus antibody
    • GNAS1 antibody
    • GPSA antibody
    • Gs alpha subunit antibody
    • GSA antibody
    • GSP antibody
    • Guanine nucleotide binding protein (G protein) alpha stimulating activity polypeptide 1 antibody
    • Guanine nucleotide binding protein alpha stimulating activity polypeptide 1 antibody
    • Guanine nucleotide binding protein G(s) subunit alpha isoforms short antibody
    • Guanine nucleotide binding protein G(s) subunit alpha isoforms XLas antibody
    • Guanine nucleotide regulatory protein antibody
    • MGC33735 antibody
    • NESP antibody
    • NESP55 antibody
    • Neuroendocrine secretory protein antibody
    • PHP1A antibody
    • PHP1B antibody
    • PHP1C antibody
    • POH antibody
    • Protein ALEX antibody
    • Protein GNAS antibody
    • Protein NESP55 antibody
    • SCG6 antibody
    • Secretogranin VI antibody
    • XLalphas antibody
    • XLas antibody
    see all

Anti-G protein alpha S antibody images

  • Anti-G protein alpha S antibody (ab101736) at 1 µg/ml + Jurkat cell lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 46 kDa
  • All lanes : Anti-G protein alpha S antibody (ab101736) at 0.1 µg/ml

    Lane 1 : Mouse Brain lysate in RIPA buffer
    Lane 2 : Rat Brain lysate in RIPA buffer

    Lysates/proteins at 35 µg per lane.


    Predicted band size : 46 kDa

References for Anti-G protein alpha S antibody (ab101736)

ab101736 has not yet been referenced specifically in any publications.

Product Wall

DISCOUNT CODE:XXXXX Expiration date: I am very pleased to hear you would like to accept our offer and test ab101736 in ICC. This code will give you 1 free PRIMARY ANTIBODY before the expiration date. To redeem this offer, please submit an Abreview for...

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Thank you for contacting Abcam. Have you already purchased the product? If so, do you have the order number used? It is usually the case that the 100% Abreview discount must be created prior to purchase of the antibody to be tested. I look forward to y...

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Thank you very much for your interest in ab101736. I would recommend that when starting this procedure that you use an ice cold methanol or acetone fixation. Fixation times can vary from 1-10 minutes so it may be best to do a series of different times....

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Thank you very much for your interest in ab101736. This particular antibody has been tested in Western Blot but to our knowledge, ab101736 has not been tested in ICC. Therefore, I can offer a discount off a future purchase if you buy ab101736 now, test...

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Thank you for contacting us. The Anti-G protein alpha S antibody ab101736 will not recognize G alpha olf or other G protein subunits. The immunizing peptide only matches with mouse GNAS NP_034439.2 and GNASL NP_963910.1 (both GeneID 14683). I hope this...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"