FunctionProbably involved in EGF and insulin receptor signaling.
Sequence similaritiesBelongs to the GAB family. Contains 1 PH domain.
Post-translational modificationsPhosphorylated on tyrosine residue(s) by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains.
Detection of GAB1 by Western Blot of Immunprecipitate.
ab117774 at 1µg/ml staining GAB1 in HeLa whole cell lysate immunoprecipitated using ab117774 at 6µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Detection: Chemiluminescence with exposure time of 30 seconds.
References for Anti-GAB1 antibody (ab117774)
has not yet been referenced specifically in any publications.
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