Overview

  • Product nameAnti-GAB1 antibody [Y423]
    See all GAB1 primary antibodies
  • Description
    Rabbit monoclonal [Y423] to GAB1
  • SpecificityThis antibody is specific for the splice isoform 2 of human GAB1.
  • Tested applicationsSuitable for: WB, ICC/IFmore details
    Unsuitable for: Flow Cyt,IHC or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human GAB1.

  • Positive control
    • 293 cell lysate.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

     

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Alternative versions available:

    Anti-GAB1 antibody (Alexa Fluor® 488) [Y423] (ab208232)

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab32093 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 76 kDa.
ICC/IF 1/50.
  • Application notesIs unsuitable for Flow Cyt,IHC or IP.
  • Target

    • FunctionProbably involved in EGF and insulin receptor signaling.
    • Sequence similaritiesBelongs to the GAB family.
      Contains 1 PH domain.
    • Post-translational
      modifications
      Phosphorylated on tyrosine residue(s) by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains.
    • Information by UniProt
    • Database links
    • Alternative names
      • Gab 1 antibody
      • GAB1 antibody
      • GAB1_HUMAN antibody
      • GRB 2 associated binder 1 antibody
      • GRB 2 associated binding protein 1 antibody
      • GRB2 associated binding protein 1 isoform a antibody
      • GRB2 associated binding protein 1 isoform b antibody
      • GRB2-associated binder 1 antibody
      • GRB2-associated-binding protein 1 antibody
      • Growth factor receptor bound protein 2-associated protein 1 antibody
      see all

    Anti-GAB1 antibody [Y423] images

    • Anti-GAB1 antibody [Y423] (ab32093) at 1/5000 dilution + 293 cell lysate.

      Predicted band size : 76 kDa
      Observed band size : 76 kDa
    • ab32093 at a 1:50 dilution staining GAB1 in PC-12 cells using immunofluoresence

    References for Anti-GAB1 antibody [Y423] (ab32093)

    This product has been referenced in:
    • Le Goff A  et al. Anti-apoptotic Role of Caspase-cleaved GAB1 Adaptor Protein in Hepatocyte Growth Factor/Scatter Factor-MET Receptor Protein Signaling. J Biol Chem 287:35382-96 (2012). WB . Read more (PubMed: 22915589) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"