Anti-GABA A Receptor alpha 2 antibody (ab49143)

Overview

  • Product nameAnti-GABA A Receptor alpha 2 antibody
    See all GABA A Receptor alpha 2 primary antibodies
  • Description
    Rabbit polyclonal to GABA A Receptor alpha 2
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Cat, Dog
  • Immunogen

    A region within synthetic peptide: PLKFGSYAYT TSEVTYIWTY NASDSVQVAP DGSRLNQYDL LGQSIGKETI, corresponding to internal sequence amino acids 181-230 of Human GABA A Receptor alpha 2

  • Positive control
    • Jurkat whole cell lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab49143 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
WB Use a concentration of 1 µg/ml. Detects a band of approximately 51 kDa (predicted molecular weight: 51 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionGABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
  • Sequence similaritiesBelongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA2 sub-subfamily.
  • Cellular localizationCell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • GABA A receptor subunit alpha 2 antibody
    • GABA antibody
    • GABA(A) receptor subunit alpha 2 antibody
    • GABA(A) receptor subunit alpha-2 antibody
    • GABR A2 antibody
    • GABRA 2 antibody
    • GABRA2 antibody
    • GABRA2 protein antibody
    • Gamma aminobutyric acid (GABA) A receptor alpha 2 antibody
    • Gamma aminobutyric acid A receptor alpha 2 antibody
    • Gamma aminobutyric acid receptor alpha 2 subunit antibody
    • Gamma aminobutyric acid receptor subunit alpha 2 antibody
    • Gamma-aminobutyric acid receptor subunit alpha-2 antibody
    • GBRA2_HUMAN antibody
    see all

Anti-GABA A Receptor alpha 2 antibody images

  • Anti-GABA A Receptor alpha 2 antibody (ab49143) at 1/100 dilution + Jurkat whole cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50,000

    Predicted band size : 51 kDa
    Observed band size : 51 kDa

References for Anti-GABA A Receptor alpha 2 antibody (ab49143)

ab49143 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"