Overview

  • Product nameAnti-GABA A Receptor alpha 2 antibody
    See all GABA A Receptor alpha 2 primary antibodies
  • Description
    Rabbit polyclonal to GABA A Receptor alpha 2
  • Specificityab72445 is specific for GABA A Receptor alpha 2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat
    Predicted to work with: Cow, Dog, Human, Non Human Primates, Zebrafish
  • Immunogen

    Fusion protein from the cytoplasmic loop of rat GABA A Receptor alpha 2

  • Positive control
    • rat brain lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab72445 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 51 kDa (predicted molecular weight: 51 kDa).

Target

  • FunctionGABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
  • Sequence similaritiesBelongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA2 sub-subfamily.
  • Cellular localizationCell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • GABA A receptor subunit alpha 2 antibody
    • GABA antibody
    • GABA(A) receptor subunit alpha 2 antibody
    • GABA(A) receptor subunit alpha-2 antibody
    • GABR A2 antibody
    • GABRA 2 antibody
    • GABRA2 antibody
    • GABRA2 protein antibody
    • Gamma aminobutyric acid (GABA) A receptor alpha 2 antibody
    • Gamma aminobutyric acid A receptor alpha 2 antibody
    • Gamma aminobutyric acid receptor alpha 2 subunit antibody
    • Gamma aminobutyric acid receptor subunit alpha 2 antibody
    • Gamma-aminobutyric acid receptor subunit alpha-2 antibody
    • GBRA2_HUMAN antibody
    see all

Anti-GABA A Receptor alpha 2 antibody images

  • All lanes : Anti-GABA A Receptor alpha 2 antibody (ab72445) at 1/1000 dilution

    Lane 1 : Wild type Mouse brain lysates
    Lane 2 : GABA A Receptor alpha 2 knockout mouse brain lysate


    Predicted band size : 51 kDa
    Observed band size : 51 kDa

References for Anti-GABA A Receptor alpha 2 antibody (ab72445)

This product has been referenced in:
  • Zhou C  et al. Altered cortical GABAA receptor composition, physiology, and endocytosis in a mouse model of a human genetic absence epilepsy syndrome. J Biol Chem 288:21458-72 (2013). WB . Read more (PubMed: 23744069) »
  • Faroni A  et al. Expression of Functional ?-Aminobutyric Acid Type A Receptors in Schwann-Like Adult Stem Cells. J Mol Neurosci : (2012). WB ; Human . Read more (PubMed: 22215379) »

See all 2 Publications for this product

Product Wall

Thank you for contacting Abcam regarding the immunogen information for ab72445 and ab103707.

Regarding ab103707, the immunogen was generated from a peptide within aa53-83, corresponding to an extracellular domain of the protein. The specific a...

Read More

Thank you for your reply.

There are few protocol variations that may help improve the results that your are getting:

1 - Do not heat/boil your samples. When looking at transmembrane proteins, it is advisable to not heat the sample a...

Read More

Thank you for contacting Abcam.

I would be more than happy to help out in any way that I can. I just have a few more protocol questions for you:

1 - Are you boiling your samples? If so for how long?

2 - What percentage of...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"