Anti-GABA A Receptor alpha 4 antibody (ab117080)

Overview

  • Product nameAnti-GABA A Receptor alpha 4 antibody
    See all GABA A Receptor alpha 4 primary antibodies
  • Description
    Goat polyclonal to GABA A Receptor alpha 4
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide:

    C-EKAKRKTSKPPQE

    (with a Cysteine residue linker), corresponding to internal sequence amino acids 349-361 of Human GABA A Receptor alpha 4 (NP_000800.2).

  • Positive control
    • Human Frontal Cortex lysate and Human Brain, Cortex tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab117080 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 62 kDa.
ELISA 1/16000.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionGABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
  • Sequence similaritiesBelongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA4 sub-subfamily.
  • Cellular localizationCell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • GABA(A) receptor subunit alpha 4 antibody
    • GABA(A) receptor subunit alpha-4 antibody
    • GABR A4 antibody
    • GABRA 4 antibody
    • Gabra4 antibody
    • Gamma aminobutyric acid (GABA) A receptor alpha 4 antibody
    • Gamma aminobutyric acid A receptor alpha 4 antibody
    • Gamma aminobutyric acid receptor alpha 4 subunit antibody
    • Gamma aminobutyric acid receptor subunit alpha 4 antibody
    • Gamma-aminobutyric acid receptor subunit alpha-4 antibody
    • GBRA4_HUMAN antibody
    see all

Anti-GABA A Receptor alpha 4 antibody images

  • Anti-GABA A Receptor alpha 4 antibody (ab117080) at 0.1 µg/ml + Human Frontal Cortex lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 62 kDa
  • Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with ab117080 followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References for Anti-GABA A Receptor alpha 4 antibody (ab117080)

ab117080 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"