Overview

  • Product nameAnti-GABA A Receptor alpha 4 antibody
    See all GABA A Receptor alpha 4 primary antibodies
  • Description
    Rabbit polyclonal to GABA A Receptor alpha 4
  • Tested applicationsSuitable for: IHC-P, WB, IPmore details
  • Species reactivity
    Reacts with: Mouse, Rat
  • Immunogen

    Fusion protein of MBP with the amino acid sequence representing the cytosolic loop of the rat GABA-A receptor alpha 4 subunit.

Properties

Applications

Our Abpromise guarantee covers the use of ab4120 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration. PubMed: 18539546
WB 1/1000. Predicted molecular weight: 66 kDa.
IP Use at an assay dependent concentration.

Target

  • FunctionGABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
  • Sequence similaritiesBelongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA4 sub-subfamily.
  • Cellular localizationCell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • GABA(A) receptor subunit alpha 4 antibody
    • GABA(A) receptor subunit alpha-4 antibody
    • GABR A4 antibody
    • GABRA 4 antibody
    • Gabra4 antibody
    • Gamma aminobutyric acid (GABA) A receptor alpha 4 antibody
    • Gamma aminobutyric acid A receptor alpha 4 antibody
    • Gamma aminobutyric acid receptor alpha 4 subunit antibody
    • Gamma aminobutyric acid receptor subunit alpha 4 antibody
    • Gamma-aminobutyric acid receptor subunit alpha-4 antibody
    • GBRA4_HUMAN antibody
    see all

Anti-GABA A Receptor alpha 4 antibody images

References for Anti-GABA A Receptor alpha 4 antibody (ab4120)

This product has been referenced in:
  • Zhang W  et al. Effect of "jian-pi-zhi-dong decoction" on gamma-aminobutyric Acid in a mouse model of tourette syndrome. Evid Based Complement Alternat Med 2014:407509 (2014). IHC-P ; Mouse . Read more (PubMed: 24812567) »
  • Quadrato G  et al. Modulation of GABAA Receptor Signaling Increases Neurogenesis and Suppresses Anxiety through NFATc4. J Neurosci 34:8630-45 (2014). Read more (PubMed: 24948817) »

See all 4 Publications for this product

Product Wall

Thank you for your enquiry. For a negative control in IP, possible suggestions are using another polyclonal from the same species (in this case a non-relevant rabbit polyclonal), or non-immune rabbit serum. If you have any additional questions, please ...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"