Anti-GABA A Receptor alpha 4 antibody (ab81525)

Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab81525 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    WB: Use at a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 66 kDa.
    Peptide ELISA: antibody detection limit dilution 1:16,000.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
    • Sequence similarities
      Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA4 sub-subfamily.
    • Cellular localization
      Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • GABA(A) receptor subunit alpha 4 antibody
      • GABA(A) receptor subunit alpha-4 antibody
      • GABR A4 antibody
      • GABRA 4 antibody
      • Gabra4 antibody
      • Gamma aminobutyric acid (GABA) A receptor alpha 4 antibody
      • Gamma aminobutyric acid A receptor alpha 4 antibody
      • Gamma aminobutyric acid receptor alpha 4 subunit antibody
      • Gamma aminobutyric acid receptor subunit alpha 4 antibody
      • Gamma-aminobutyric acid receptor subunit alpha-4 antibody
      • GBRA4_HUMAN antibody
      see all

    Images

    • Anti-GABA A Receptor alpha 4 antibody (ab81525) at 0.1 µg/ml (for 1 hour) + Human Frontal Cortex lysate in RIPA buffer at 35 µg
      Developed using the ECL technique

      Predicted band size : 66 kDa
      Observed band size : 75 kDa (why is the actual band size different from the predicted?)

    References

    ab81525 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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