Anti-GABA A Receptor alpha 6 antibody (ab117100)

Overview

  • Product nameAnti-GABA A Receptor alpha 6 antibody
    See all GABA A Receptor alpha 6 primary antibodies
  • Description
    Goat polyclonal to GABA A Receptor alpha 6
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Dog
  • Immunogen

    Synthetic peptide:

    HPDSKYHLKKR

    with a Cysteine residue linker, corresponding to internal sequence amino acids 363-373 of Human GABA A Receptor alpha 6 (NP_000802.2).

  • Positive control
    • Human brain (cortex) tissue; Human cerebellum lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab117100 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 51 kDa.
ELISA Use a concentration of 1 - 3 µg/ml.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionGABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
  • Sequence similaritiesBelongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA6 sub-subfamily.
  • Cellular localizationCell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • GABA A antibody
    • GABA A Receptor alpha 6 polypeptide antibody
    • GABA A receptor alpha 6 antibody
    • GABA A receptor subunit alpha 6 antibody
    • GABA subunit A receptor alpha 6 antibody
    • GABA(A) receptor subunit alpha-6 antibody
    • GABRA 6 antibody
    • GABRA6 antibody
    • Gamma aminobutyric acid A receptor alpha 6 antibody
    • Gamma aminobutyric acid GABA A receptor alpha 6 antibody
    • Gamma aminobutyric acid receptor subunit alpha 6 antibody
    • Gamma-aminobutyric acid receptor subunit alpha-6 antibody
    • GBRA6_HUMAN antibody
    • MGC116903 antibody
    • MGC116904 antibody
    see all

Anti-GABA A Receptor alpha 6 antibody images

  • Anti-GABA A Receptor alpha 6 antibody (ab117100) at 1 µg/ml + Human cerebellum lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 51 kDa
  • ab117100 at 2.5ug/ml staining GABA A Receptor alpha 6 in Formalin-fixed, Paraffin-embedded Human brain (cortex) tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References for Anti-GABA A Receptor alpha 6 antibody (ab117100)

ab117100 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"