Overview

  • Product nameAnti-GABA A Receptor beta 1 antibody
    See all GABA A Receptor beta 1 primary antibodies
  • Description
    Rabbit polyclonal to GABA A Receptor beta 1
  • SpecificityReacts with the 51-54 kDa beta 1 subunit of rat brain GABA A. There is no homology or known reactivity with other GABA subunits.
  • Tested applicationsSuitable for: IHC-P, WB, IPmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Fusion protein of MBP with the amino acid sequence representing the cytosolic loop of the rat GABA A receptor beta 1 subunit.

  • Positive control
    • rat forebrain lysate, rat cerebellum or cortex lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab16703 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration. PubMed: 18539546
WB 1/1000. Predicted molecular weight: 53 kDa.
IP Use at an assay dependent concentration. Use at an assay dependent dilution. 15 ug of antibody were used to IP 24% of all GABA-A receptors in dodecylsulfate extracts of rat forebrains (150 ul).

Target

  • FunctionGABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
  • Sequence similaritiesBelongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB1 sub-subfamily.
  • Cellular localizationCell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • AW061132 antibody
    • B230208N19Rik antibody
    • GABA(A) receptor beta 1 antibody
    • GABA(A) receptor subunit beta-1 antibody
    • GABA-A receptor, beta-1 polypeptide antibody
    • Gabrb-1 antibody
    • GABRB1 antibody
    • Gamma aminobutyric acid (GABA) A receptor beta 1 antibody
    • Gamma Aminobutyric Acid A Receptor Beta 1 antibody
    • Gamma Aminobutyric Acid Receptor , beta-1 antibody
    • Gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 antibody
    • Gamma-aminobutyric acid receptor subunit beta-1 antibody
    • GARB1 antibody
    • GBRB1_HUMAN antibody
    see all

Anti-GABA A Receptor beta 1 antibody images

  • All lanes : Anti-GABA A Receptor beta 1 antibody (ab16703) at 1/1000 dilution

    Lane 1 : Cerebellum lysate
    Lane 2 : Cortex lysate


    Predicted band size : 53 kDa
    Observed band size : 51 kDa (why is the actual band size different from the predicted?)

References for Anti-GABA A Receptor beta 1 antibody (ab16703)

This product has been referenced in:
  • Quintana A  et al. Lack of GPR88 enhances medium spiny neuron activity and alters motor- and cue-dependent behaviors. Nat Neurosci 15:1547-55 (2012). Mouse . Read more (PubMed: 23064379) »
  • Adusei DC  et al. Early developmental alterations in GABAergic protein expression in fragile X knockout mice. Neuropharmacology 59:167-71 (2010). WB ; Mouse . Read more (PubMed: 20470805) »

See all 3 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"