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Rabbit polyclonal to GABA A Receptor beta 1
Reacts with the 51-54 kDa beta 1 subunit of rat brain GABA A. There is no homology or known reactivity with other GABA subunits.
Mouse, Rat, Human
Fusion protein of MBP with the amino acid sequence representing the cytosolic loop of the rat GABA A receptor beta 1 subunit.
- rat forebrain lysate, rat cerebellum or cortex lysate
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 50% Glycerol, 100µg/ml BSA, 150mM Sodium chloride, 10mM HEPES. pH 7.5
Concentration information loading...
Protein A purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use at an assay dependent concentration. PubMed: 18539546
||1/1000. Predicted molecular weight: 53 kDa.
||Use at an assay dependent concentration. Use at an assay dependent dilution. 15 ug of antibody were used to IP 24% of all GABA-A receptors in dodecylsulfate extracts of rat forebrains (150 ul).
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB1 sub-subfamily.
Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
Information by UniProt
- AW061132 antibody
- B230208N19Rik antibody
- GABA(A) receptor beta 1 antibody
Anti-GABA A Receptor beta 1 antibody images
Western blot - GABA A Receptor beta 1 antibody (ab16703)
References for Anti-GABA A Receptor beta 1 antibody (ab16703)
This product has been referenced in:
- Quintana A et al. Lack of GPR88 enhances medium spiny neuron activity and alters motor- and cue-dependent behaviors. Nat Neurosci 15:1547-55 (2012).
Read more (PubMed: 23064379) »
- Adusei DC et al. Early developmental alterations in GABAergic protein expression in fragile X knockout mice. Neuropharmacology 59:167-71 (2010).
Read more (PubMed: 20470805) »
See all 3 Publications
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"