Anti-GABA A Receptor beta 1 antibody [N96/55] (ab93612)

Overview

  • Product name
    Anti-GABA A Receptor beta 1 antibody [N96/55]
    See all GABA A Receptor beta 1 primary antibodies
  • Description
    Mouse monoclonal [N96/55] to GABA A Receptor beta 1
  • Specificity
    No cross-reactivity against GABA A Receptor beta 2 or GABA A Receptor beta 3.
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Fusion protein, corresponding to C terminal amino acids 327 - 450 of Mouse GABA A Receptor beta 1 (Acc. No. P50571).

  • Positive control
    • WB: rat brain lysate
  • General notes

    The clone number has been updated from S96-55 to N96/55, both clone numbers name the same antibody clone.

     

Properties

Applications

Our Abpromise guarantee covers the use of ab93612 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 10 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 54 kDa).
ICC/IF Use a concentration of 1 - 10 µg/ml. [ 0.1 - 1 µg/mL (Perox), 1 - 10 µg/mL (IF) ]

Target

  • Function
    GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
  • Sequence similarities
    Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB1 sub-subfamily.
  • Cellular localization
    Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • AW061132 antibody
    • B230208N19Rik antibody
    • GABA(A) receptor beta 1 antibody
    • GABA(A) receptor subunit beta-1 antibody
    • GABA-A receptor, beta-1 polypeptide antibody
    • Gabrb-1 antibody
    • GABRB1 antibody
    • Gamma aminobutyric acid (GABA) A receptor beta 1 antibody
    • Gamma Aminobutyric Acid A Receptor Beta 1 antibody
    • Gamma Aminobutyric Acid Receptor , beta-1 antibody
    • Gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 antibody
    • Gamma-aminobutyric acid receptor subunit beta-1 antibody
    • GARB1 antibody
    • GBRB1_HUMAN antibody
    see all

Images



  • Predicted band size : 54 kDa
    Western blot detection of GABA A Receptor beta 1 in Rat brain membrane lysates using ab96612 at 1:1000 dilution.

References

This product has been referenced in:
  • Bates RC  et al. Reduced CHRNA7 expression in C3H mice is associated with increases in hippocampal parvalbumin and glutamate decarboxylase-67 (GAD67) as well as altered levels of GABA(A) receptor subunits. Neuroscience 273:52-64 (2014). Read more (PubMed: 24836856) »

See 1 Publication for this product

Customer reviews and Q&As

Thank you for contacting us.
Upon checking with the lab, they confirmed that any type of IHC has not yet been tested with this antibody so far. I apologize for any inconveniences caused.

Thus, if your colleagues had problems with this an...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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