Overview

  • Product name
    Anti-GABA A Receptor beta 2 antibody
    See all GABA A Receptor beta 2 primary antibodies
  • Description
    Rabbit polyclonal to GABA A Receptor beta 2
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant fragment corresponding to Human GABA A Receptor beta 2 aa 26-244.
    Database link: P47870

  • Positive control
    • Mouse liver tissue extract

Properties

Applications

Our Abpromise guarantee covers the use of ab186875 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 59 kDa.
IHC-P 1/50 - 1/200.

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

Target

  • Function
    GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
  • Tissue specificity
    Isoform 1 and isoform 2 show reduced expression in schizophrenic brain. Isoform 3 shows increased expression in schizophrenic and bipolar disorder brains while isoform 4 shows reduced expression.
  • Sequence similarities
    Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB2 sub-subfamily.
  • Cellular localization
    Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • GABA antibody
    • GABA(A) receptor beta 2 antibody
    • GABA(A) receptor subunit beta-2 antibody
    • GABA-A receptor, beta-2 polypeptide antibody
    • GABRB2 antibody
    • Gamma aminobutyric acid (GABA) A receptor, beta 2 antibody
    • Gamma aminobutyric acid A receptor beta 2 antibody
    • Gamma-aminobutyric acid receptor subunit beta-2 antibody
    • Gamma-aminobutyric-acid receptor subunit beta-2 antibody
    • GBRB2_HUMAN antibody
    see all

Images

  • Anti-GABA A Receptor beta 2 antibody (ab186875) at 1/500 dilution + Mouse liver tissue extract

    Predicted band size: 59 kDa

References

This product has been referenced in:
  • Konermann A  et al. Verification of ?-Amino-Butyric Acid (GABA) Signaling System Components in Periodontal Ligament Cells In Vivo and In Vitro. Cell Mol Neurobiol 36:1353-1363 (2016). Read more (PubMed: 26865191) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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