Anti-GABA A Receptor beta 2 antibody (ab42598)

Overview

  • Product nameAnti-GABA A Receptor beta 2 antibody
    See all GABA A Receptor beta 2 primary antibodies
  • Description
    Rabbit polyclonal to GABA A Receptor beta 2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region of Human GABRB2. More details of the immunogen are not available.

  • Positive control
    • HepG2 cell lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab42598 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 µg/ml. Predicted molecular weight: 55 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionGABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
  • Tissue specificityIsoform 1 and isoform 2 show reduced expression in schizophrenic brain. Isoform 3 shows increased expression in schizophrenic and bipolar disorder brains while isoform 4 shows reduced expression.
  • Sequence similaritiesBelongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB2 sub-subfamily.
  • Cellular localizationCell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • GABA antibody
    • GABA(A) receptor beta 2 antibody
    • GABA(A) receptor subunit beta-2 antibody
    • GABA-A receptor, beta-2 polypeptide antibody
    • GABRB2 antibody
    • Gamma aminobutyric acid (GABA) A receptor, beta 2 antibody
    • Gamma aminobutyric acid A receptor beta 2 antibody
    • Gamma-aminobutyric acid receptor subunit beta-2 antibody
    • Gamma-aminobutyric-acid receptor subunit beta-2 antibody
    • GBRB2_HUMAN antibody
    see all

Anti-GABA A Receptor beta 2 antibody images

  • All lanes : Anti-GABA A Receptor beta 2 antibody (ab42598) at 0.5 µg/ml

    Lane 1 : Marker
    Lane 2 : HepG2 Cell Lysate


    Predicted band size : 55 kDa
    Observed band size : 52 kDa (why is the actual band size different from the predicted?)

References for Anti-GABA A Receptor beta 2 antibody (ab42598)

ab42598 has not yet been referenced specifically in any publications.

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