Anti-GABA A receptor pi antibody (ab116109)

Overview

  • Product nameAnti-GABA A receptor pi antibody
    See all GABA A receptor pi primary antibodies
  • Description
    Rabbit polyclonal to GABA A receptor pi
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Human
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 40-89 (GFENLTAGYN KFLRPNFGGD PVRIALTLDI ASISSISESN MDYTATIYLR) of Mouse GABA A receptor pi (NP_666129).

  • Positive control
    • Mouse Kidney lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab116109 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 50 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionGABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. In the uterus, the function of the receptor appears to be related to tissue contractility. The binding of this pI subunit with other GABA(A) receptor subunits alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone.
  • Tissue specificityMost abundant in the uterus, also expressed in lung, thymus and prostate.
  • Sequence similaritiesBelongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRP sub-subfamily.
  • Cellular localizationCell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • GABA(A) receptor subunit pi antibody
    • GABRP antibody
    • Gamma aminobutyric acid (GABA) A receptor pi antibody
    • Gamma aminobutyric acid A receptor pi antibody
    • Gamma aminobutyric acid receptor pi subunit antibody
    • Gamma aminobutyric acid receptor subunit pi antibody
    • Gamma-aminobutyric acid receptor subunit pi antibody
    • GBRP_HUMAN antibody
    • MGC126386 antibody
    • MGC126387 antibody
    see all

Anti-GABA A receptor pi antibody images

  • Anti-GABA A receptor pi antibody (ab116109) at 1 µg/ml + Mouse Kidney Lysate at 10 µg

    Predicted band size : 50 kDa

References for Anti-GABA A receptor pi antibody (ab116109)

ab116109 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"