Anti-GABA Transporter 1 / GAT 1 antibody (ab102110)

Overview

  • Product nameAnti-GABA Transporter 1 / GAT 1 antibody
    See all GABA Transporter 1 / GAT 1 primary antibodies
  • Description
    Rabbit polyclonal to GABA Transporter 1 / GAT 1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide (LIILFFRGVT LPGAKEGILF YITPNFRKLS DSEVWLDAAT QIFFSYGLGL) corresponding to a region within internal sequence amino acids 251-300 of Human GABA Transporter 1/ GAT 1 (NP_003033).

  • Positive control
    • HepG2 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab102110 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 67 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionTerminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.
  • Sequence similaritiesBelongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A1 subfamily.
  • DomainThe PDZ domain-binding motif is involved in the interaction with MPP5.
  • Cellular localizationCell membrane. Membrane. Localized at the plasma membrane and in a subset of intracellular vesicles. Localized at the presynaptic terminals of interneurons.
  • Information by UniProt
  • Database links
  • Alternative names
    • GABATHG antibody
    • GABATR antibody
    • GABT 1 antibody
    • GABT1 antibody
    • GAT-1 antibody
    • GAT1 antibody
    • SC6A1_HUMAN antibody
    • Slc6a1 antibody
    • Sodium and chloride dependent GABA transporter 1 antibody
    • Sodium- and chloride-dependent GABA transporter 1 antibody
    • Solute carrier family 6 (neurotransmitter transporter GABA) member 1 antibody
    • Solute carrier family 6 member 1 antibody
    see all

Anti-GABA Transporter 1 / GAT 1 antibody images

  • Anti-GABA Transporter 1 / GAT 1 antibody (ab102110) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Predicted band size : 67 kDa

References for Anti-GABA Transporter 1 / GAT 1 antibody (ab102110)

ab102110 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry (Frozen sections)
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 23°C
Sample Zebrafish Tissue sections (Retina)
Specification Retina
Permeabilization No
Fixative Paraformaldehyde
Username

Dr. Ryan MacDonald

Verified customer

Submitted Jul 30 2013

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"