Anti-GABA Transporter 3 / GAT 3 antibody (ab122430)

Overview

  • Product name
    Anti-GABA Transporter 3 / GAT 3 antibody
    See all GABA Transporter 3 / GAT 3 primary antibodies
  • Description
    Rabbit polyclonal to GABA Transporter 3 / GAT 3
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: GTLPEKLQKL TTPSTDLKMR GKLGVSPRMV TVNDCDAKLK SDGTIAAITE KETHF, corresponding to C terminal amino acids 578-632 of Human GABA Transporter 3/ GAT 3 (UniProt ID: P48066).

  • Positive control
    • Human pancreas tissue; Human tonsil lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab122430 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

Target

  • Function
    Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.
  • Tissue specificity
    Widespread distribution in the brain.
  • Sequence similarities
    Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A11 subfamily.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • GABT3 antibody
    • GAT-3 antibody
    • GAT3 antibody
    • S6A11_HUMAN antibody
    • Slc6a11 antibody
    • Sodium- and chloride-dependent GABA transporter 3 antibody
    • Solute carrier family 6 member 11 antibody
    see all

Images

  • All lanes : Anti-GABA Transporter 3 / GAT 3 antibody (ab122430) at 1/250 dilution

    Lane 1 : RT-4 cell lysate
    Lane 2 : U-251 MG cell lysate
    Lane 3 : Human plasma lysate
    Lane 4 : Human liver lysate
    Lane 5 : Human tonsil lysate
  • ab122430, at a 1/50 dilution, staining GABA Transporter 3 / GAT 3 in paraffin embedded Human pancreas tissue by Immunohistochemistry.

References

ab122430 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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