Anti-GAD65 antibody, prediluted (ab15299)

Overview

  • Product nameAnti-GAD65 antibody, prediluted
    See all GAD65 primary antibodies
  • Description
    Rabbit polyclonal to GAD65, prediluted
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (C terminal).

  • Positive control
    • Human Pancreas.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab15299 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • FunctionCatalyzes the production of GABA.
  • Sequence similaritiesBelongs to the group II decarboxylase family.
  • Post-translational
    modifications
    Phosphorylated; which does not affect kinetic parameters or subcellular location.
    Palmitoylated; which is required for presynaptic clustering.
  • Cellular localizationCytoplasm > cytosol. Cytoplasmic vesicle. Cell junction > synapse > presynaptic cell membrane. Golgi apparatus membrane. Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters.
  • Information by UniProt
  • Database links
  • Alternative names
    • 65 kDa glutamic acid decarboxylase antibody
    • DCE 2 antibody
    • DCE2 antibody
    • DCE2_HUMAN antibody
    • GAD 2 antibody
    • GAD 65 antibody
    • GAD-2 antibody
    • GAD-65 antibody
    • Gad2 antibody
    • Glutamate decarboxylase 2 (pancreas) antibody
    • Glutamate Decarboxylase 2 (pancreatic islets and brain 65kDa) antibody
    • Glutamate decarboxylase 2 antibody
    • Glutamate Decarboxylase 65 antibody
    • Glutamate decarboxylase 65 kDa isoform antibody
    • Glutamic Acid Decarboxylase 2 antibody
    • Glutamic Acid Decarboxylase 65 antibody
    • MGC161605 antibody
    • MGC161607 antibody
    see all

Anti-GAD65 antibody, prediluted images

  • ab15299 staining GAD65 in human pancreas by Immunohistochemistry (FFPE-sections).

References for Anti-GAD65 antibody, prediluted (ab15299)

ab15299 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry and I'm sorry to hear that you are experiencing difficulty with these antibodies. I saw that my colleague Charlotte previously made the following suggestion to you - "From the information that you have forwarded I suspect tha...

Read More

Thank you for your enquiry and you patience in awaiting a response. From the information that you have forwarded I suspect that the non specific binding may be due to the fact that you have not blocked endogenous tissue peroxidase activity. This is imp...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"