Anti-GADD45B antibody (ab205252)
Key features and details
- Rabbit polyclonal to GADD45B
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-GADD45B antibody
See all GADD45B primary antibodies -
Description
Rabbit polyclonal to GADD45B -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Cow -
Immunogen
Recombinant full length protein corresponding to Human GADD45B aa 1 to the C-terminus. BC113466.
Database link: O75293 -
Positive control
- WB: HeLa cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Lyophilized:Reconstitute with 200ul distilled sterile water. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary. -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 98% PBS, 1% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab205252 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/200 - 1/1000. Predicted molecular weight: 18 kDa.
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Notes |
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WB
1/200 - 1/1000. Predicted molecular weight: 18 kDa. |
Target
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Function
Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK. -
Sequence similarities
Belongs to the GADD45 family. - Information by UniProt
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Database links
- Entrez Gene: 618405 Cow
- Entrez Gene: 4616 Human
- Entrez Gene: 17873 Mouse
- Omim: 604948 Human
- SwissProt: Q5E9A5 Cow
- SwissProt: O75293 Human
- SwissProt: P22339 Mouse
- Unigene: 110571 Human
see all -
Form
It localizes to the nucleus. -
Alternative names
- GA45B_HUMAN antibody
- GADD45 Beta antibody
- Gadd45b antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab205252 has been referenced in 3 publications.
- Zhang X et al. ALKBH5 inhibits TNF-α-induced apoptosis of HUVECs through Bcl-2 pathway. Open Med (Wars) 17:1092-1099 (2022). PubMed: 35799597
- Yu Z et al. Long Non-coding RNA FENDRR Acts as a miR-423-5p Sponge to Suppress the Treg-Mediated Immune Escape of Hepatocellular Carcinoma Cells. Mol Ther Nucleic Acids 17:516-529 (2019). PubMed: 31351327
- Lv L et al. Downregulation of Pin1 in human atherosclerosis and its association with vascular smooth muscle cell senescence. J Vasc Surg 68:873-883.e5 (2018). PubMed: 28986099