Overview

  • Product nameAnti-GADD45GIP1 antibody
    See all GADD45GIP1 primary antibodies
  • Description
    Rabbit polyclonal to GADD45GIP1
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A synthesized peptide derived from an internal region of Human GADD45GIP1.

  • Positive control
    • Human brain tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab111254 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionActs as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.
  • Tissue specificityWidely expressed. Highly expressed in the thyroid gland, heart, lymph nodes, trachea and adrenal tissues. Expressed at lower level in liver skeletal muscle, kidney, pancreas, testis, ovary and stomach. Barely detectable in adrenal adenoma and papillary thyroid cancer.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 39S ribosomal protein L59 mitochondrial antibody
    • CKBBP2 antibody
    • CKbetaBP2 antibody
    • CKII beta associating protein antibody
    • CKII beta binding protein 2 antibody
    • CKII beta-associating protein antibody
    • CR6 interacting factor 1 antibody
    • CR6-interacting factor 1 antibody
    • CRIF1 antibody
    • G45IP_HUMAN antibody
    • Gadd45gip1 antibody
    • Growth arrest and DNA damage inducible GADD45G interacting protein antibody
    • growth arrest and DNA damage inducible, gamma interacting protein 1 antibody
    • Growth arrest and DNA damage-inducible proteins-interacting protein 1 antibody
    • MGC4667 antibody
    • MGC4758 antibody
    • MRP L59 antibody
    • p53 responsive gene 6 antibody
    • p53 responsive gene 6 protein antibody
    • p53-responsive gene 6 protein antibody
    • Papillomavirus L2 interacting nuclear protein 1 antibody
    • Papillomavirus L2-interacting nuclear protein 1 antibody
    • PLINP 1 antibody
    • PLINP antibody
    • PLINP-1 antibody
    • PLINP1 antibody
    • PRG6 antibody
    see all

Anti-GADD45GIP1 antibody images

  • Immunohistochemistry analysis of paraffin-embedded Human brain tissue, using 1/50 ab111254. The picture on the right is treated with the synthesized peptide

References for Anti-GADD45GIP1 antibody (ab111254)

ab111254 has not yet been referenced specifically in any publications.

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