Overview

  • Product nameAnti-Galantide antibody (Biotin)
  • Description
    Rabbit polyclonal to Galantide (Biotin)
  • ConjugationBiotin
  • Tested applicationsSuitable for: ELISA, RIAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide: GWTLNSAGYLLGPQQFFGLM-NH2 conjugated to KLH via carboxyl group, corresponding to amino acids from Human Galantide.

Properties

Applications

Our Abpromise guarantee covers the use of ab48282 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
RIA Use at an assay dependent dilution.

Target

  • RelevanceThe galanin antagonist Galantide, a chimeric peptide obtained from amino acids 1-13 of galanin attached to the C terminal fragment of bradykinin, has been found to improve social memory in `social recognition' tests when i.c.v. administered at doses varying from 6-6000 nmoles. Galantide causes widespread antagonism to the action of galanin and reversibly blocks the neuronal actions of galanin in a dose dependent manner. It inhibits the release of acetylcholine, reduces the response to galanin in the hypothalamus, and blocks the effect of galanin on glucose induced insulin secretion.
  • Cellular localizationSecreted

References for Anti-Galantide antibody (Biotin) (ab48282)

ab48282 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"