• Product nameAnti-GALE antibody [OTI1C4]
    See all GALE primary antibodies
  • Description
    Mouse monoclonal [OTI1C4] to GALE
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Rat, Dog, Human, Monkey
  • Immunogen

    Recombinant full length Human GALE produced in HEK293T cells (NP_000394).

  • Positive control
    • HEK293T cell lysate transfected with the pCMV6-ENTRY GALE cDNA; HepG2, HeLa, HT29, A549, COS7, Jurkat, MDCK, PC12 and MCF7 cell lysates.
  • General notes

    The clone number has been updated from 1C4 to OTI1C4, both clone numbers name the same clone.



Our Abpromise guarantee covers the use of ab118033 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 38 kDa.


  • FunctionCatalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine.
  • PathwayCarbohydrate metabolism; galactose metabolism.
  • Involvement in diseaseDefects in GALE are the cause of epimerase-deficiency galactosemia (EDG) [MIM:230350]; also known as galactosemia type 3. Clinical features include early-onset cataracts, liver damage, deafness and mental retardation. There are two clinically distinct forms of EDG. (1) A benign, or 'peripheral' form with no detectable GALE activity in red blood cells and characterized by mild symptoms. Some patients may suffer no symptoms beyond raised levels of galactose-1-phosphate in the blood. (2) A much rarer 'generalized' form with undetectable levels of GALE activity in all tissues and resulting in severe features such as restricted growth and mental development.
  • Sequence similaritiesBelongs to the sugar epimerase family.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ95174 antibody
    • FLJ97302 antibody
    • Galactose 4 epimerase UDP antibody
    • Galactowaldenase antibody
    • galE antibody
    • GALE_HUMAN antibody
    • OTTHUMP00000002991 antibody
    • OTTHUMP00000002994 antibody
    • OTTHUMP00000037931 antibody
    • OTTHUMP00000044857 antibody
    • SDR1E1 antibody
    • short chain dehydrogenase/reductase family 1E member 1 antibody
    • UDP galactose 4 epimerase antibody
    • UDP galactose 4' epimerase antibody
    • UDP glucose 4 epimerase antibody
    • UDP-galactose 4-epimerase antibody
    • UDP-glucose 4-epimerase antibody
    see all

Anti-GALE antibody [OTI1C4] images

  • All lanes : Anti-GALE antibody [OTI1C4] (ab118033) at 1/500 dilution

    Lane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNA
    Lane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY GALE cDNA

    Lysates/proteins at 5 µg per lane.

    Predicted band size : 38 kDa
    HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC201561)
  • All lanes : Anti-GALE antibody [OTI1C4] (ab118033) at 1/500 dilution

    Lane 1 : HepG2 cell lysate
    Lane 2 : HeLa cell lysate
    Lane 3 : HT29 cell lysate
    Lane 4 : A549 cell lysate
    Lane 5 : COS7 cell lysate
    Lane 6 : Jurkat cell lysate
    Lane 7 : MDCK cell lysate
    Lane 8 : PC12 cell lysate
    Lane 9 : MCF7 cell lysate

    Lysates/proteins at 35 µg per lane.

    Predicted band size : 38 kDa
    HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC201561)

References for Anti-GALE antibody [OTI1C4] (ab118033)

ab118033 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab118033.
Please use the links above to contact us or submit feedback about this product.