General notesab94225 is a 293T cell transfected lysate in which Human Galectin 3 has been transiently over-expressed using a pCMV-Galectin 3 plasmid. The lysate is provided in 1X Sample Buffer.
Note: For more details about how the transfected lysate was prepared view preparation notes
BackgroundFunction: Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis.
Tissue specificity: A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages.
Similarity: Contains 1 galectin domain.