Anti-GALK1 antibody (ab14023)

Overview

• Product name
  Anti-GALK1 antibody
  See all GALK1 primary antibodies
• Description
  Chicken polyclonal to GALK1
• Tested applications
  Suitable for: WBmore details
• Species reactivity
  Reacts with: Mouse, Rat, Human
  
• Immunogen

  Full length protein (Human).

• Positive control
  • human liver cell lysate

Properties

• Form
  Liquid
• Storage instructions
  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage buffer
  Preservative: None
  Constituents: PBS
• Concentration information loading...
• Purity
  Immunogen affinity purified
• Purification notes
  Peptide immunogen affinity column
• Clonality
  Polyclonal
• Isotype
  IgY
• Research areas
  • Cell Biology
  • Cell Cycle
  • Kinases/Phosphatases
  • Other

  • Signal Transduction
  • Metabolism
  • Energy Metabolism

  • Epigenetics and Nuclear Signaling
  • Cell cycle
  • Kinases/Phosphatases
  • Other

  • Cancer
  • Cancer Metabolism
  • Metabolic signaling pathway
  • Metabolism of carbohydrates

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Carbohydrate metabolism

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Energy transfer pathways
  • Energy Metabolism

  • Metabolism
  • Types of disease
  • Cancer

Applications

Target

• Function
  Major enzyme for galactose metabolism.
• Pathway
  Carbohydrate metabolism; galactose metabolism.
• Involvement in disease
  Defects in GALK1 are the cause of galactosemia II (GALCT2) [MIM:230200]. Galactosemia II is an autosomal recessive deficiency characterized by congenital cataracts during infancy and presenile cataracts in the adult population. The cataracts are secondary to accumulation of galactitol in the lenses.
• Sequence similarities
  Belongs to the GHMP kinase family. GalK subfamily.

• Target information above from: UniProt accession P51570 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 2584 Human
  • Entrez Gene: 14635 Mouse
  • Entrez Gene: 287835 Rat
  • Omim: 604313 Human
  • SwissProt: P51570 Human
  • SwissProt: Q9R0N0 Mouse
  • Unigene: 407966 Human
  • Unigene: 2820 Mouse

  • Unigene: 198917 Rat

  see all
• Alternative names
  • EC 2.7.1.6 antibody
  • epididymis secretory protein Li 19 antibody
  • Galactokinase 1 antibody

  • Galactokinase antibody
  • Galactose kinase antibody
  • GALK 1 antibody
  • GALK antibody
  • GALK1 antibody
  • GALK1_HUMAN antibody
  • GK1 antibody
  • GLK antibody
  • GLK1 antibody
  • HEL-S-19 antibody

  see all

Protocols

• Western blot protocols